Smita Cherry, Eugene Jennifer Jin ... P Robin Hiesinger
Mutations that reduce the functioning of rab7 may underlie the degeneration of sensory and motor nerves in Charcot-Marie-Tooth 2B disease, which suggests increasing endolysosomal function as a therapy.
Computer simulations of interaural time difference decoders show that heterogeneous tuning of binaural neurons leads to accurate sound localization in natural environments.
Shawniqua T Williams, Mary M Conte ... Nicholas D Schiff
The therapeutic effects of the sleeping pill zolpidem in patients with disorders of consciousness may be due to recruitment of brain cells idling in abnormally low-frequency brain waves.
Tamar R Makin, Alona O Cramer ... Heidi Johansen-Berg
In individuals with a missing hand, the area of the brain that would otherwise control that hand is recruited by either the remaining hand or the residual limb, depending on the usage preference of the individual.
The precise position of UNC-13 at the active zone near a synapse depends on the N-terminus of the protein, and the C2A domain in particular, and is essential for accelerating neurotransmitter release.
Sean Michael Boyle, Shane McInally, Anandasankar Ray
A computational method that can screen thousands of chemicals and predict which odorants will interact with specific odorant receptors in flies may ultimately aid the development of more effective insect repellents.