Browse our latest Stem Cells and Regenerative Medicine articles

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    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    EGFR signaling promotes self-renewal through the establishment of cell polarity in Drosophila follicle stem cells

    Angela Castanieto, Michael J Johnston, Todd G Nystul
    The specification of cell polarity is essential for self-renewal and the segregation of stem-cell and daughter-cell fates in an epithelial stem cell lineage.
    1. Biochemistry and Chemical Biology
    2. Stem Cells and Regenerative Medicine

    The dyskerin ribonucleoprotein complex as an OCT4/SOX2 coactivator in embryonic stem cells

    Yick W Fong, Jaclyn J Ho ... Robert Tjian
    A previously unrecognized transcriptional coactivator function of the dyskerin ribonucleoprotein complex and its associated small nucleolar RNA has been uncovered and mediates embryonic stem cell-specific transcription.
    1. Stem Cells and Regenerative Medicine

    Trithorax maintains the functional heterogeneity of neural stem cells through the transcription factor Buttonhead

    Hideyuki Komori, Qi Xiao ... Cheng-Yu Lee
    The Drosophila equivalent of the human protein Mixed Lineage Leukemia 1n enables neural stem cells to generate neural progenitors through the fly equivalent of the human transcription factor Sp8, thereby contributing to an increased number and diversity of cell types during brain development.
    1. Stem Cells and Regenerative Medicine
    2. Immunology and Inflammation

    The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor

    Xiaofei Yu, Yuhao Wang ... Lora V Hooper
    The transcription factor NFIL3 is essential for the development of a committed bone marrow precursor that gives rise to all known innate lymphoid cell lineages in mice.
    1. Stem Cells and Regenerative Medicine

    Transient nuclear Prospero induces neural progenitor quiescence

    Sen-Lin Lai, Chris Q Doe
    A low-level pulse of the nuclear Prospero protein is necessary and sufficient to cause neural progenitor cells to enter a quiescent state.
    1. Stem Cells and Regenerative Medicine

    Quiescence: Quantitative differences, qualitative outcomes

    Giulia Pollarolo, Cayetano Gonzalez
    Version of Record
    Insight
    1. Stem Cells and Regenerative Medicine

    The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem cell niche function

    Joan Isern, Andrés García-García ... Simón Méndez-Ferrer
    Developing long bones contain distinct mesenchymal stem-cell populations derived from mesoderm and neural crest, which have specialized functions in skeleton formation and the establishment of the hematopoietic stem-cell niche, respectively.
    1. Stem Cells and Regenerative Medicine

    Identification of a new stem cell population that generates Drosophila flight muscles

    Rajesh D Gunage, Heinrich Reichert, K VijayRaghavan
    Large flight muscle of Drosophila are made by the regulated amplification of a newly identified stem cell population.