Browse our latest Stem Cells and Regenerative Medicine articles

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    1. Stem Cells and Regenerative Medicine

    Transient nuclear Prospero induces neural progenitor quiescence

    Sen-Lin Lai, Chris Q Doe
    A low-level pulse of the nuclear Prospero protein is necessary and sufficient to cause neural progenitor cells to enter a quiescent state.
    1. Stem Cells and Regenerative Medicine

    Quiescence: Quantitative differences, qualitative outcomes

    Giulia Pollarolo, Cayetano Gonzalez
    Version of Record
    Insight
    1. Stem Cells and Regenerative Medicine

    The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem cell niche function

    Joan Isern, Andrés García-García ... Simón Méndez-Ferrer
    Developing long bones contain distinct mesenchymal stem-cell populations derived from mesoderm and neural crest, which have specialized functions in skeleton formation and the establishment of the hematopoietic stem-cell niche, respectively.
    1. Stem Cells and Regenerative Medicine

    Identification of a new stem cell population that generates Drosophila flight muscles

    Rajesh D Gunage, Heinrich Reichert, K VijayRaghavan
    Large flight muscle of Drosophila are made by the regulated amplification of a newly identified stem cell population.
    1. Stem Cells and Regenerative Medicine
    2. Chromosomes and Gene Expression

    Mof-associated complexes have overlapping and unique roles in regulating pluripotency in embryonic stem cells and during differentiation

    Sarina Ravens, Marjorie Fournier ... Làszlò Tora
    Two complexes that contain the histone acetyl transferase MOF have distinct regulatory roles in the growth and development of pluripotent embryonic stem cells
    1. Stem Cells and Regenerative Medicine

    Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain

    John K Mich, Robert AJ Signer ... Sean J Morrison
    Flow cytometric isolation and fate mapping shows that neurosphere-initiating cells are highly mitotically active and persist only transiently in vivo, and are distinct from quiescent, long-lived neural stem cells.
    1. Stem Cells and Regenerative Medicine
    2. Neuroscience

    Distinct and separable roles for EZH2 in neurogenic astroglia

    William W Hwang, Ryan D Salinas ... Daniel A Lim
    A number of genes associated with the development of brain tumors are epigenetically repressed in specialized astrocytes to enable the production of neurons in the postnatal brain.
    1. Stem Cells and Regenerative Medicine

    Transgressions of compartment boundaries and cell reprogramming during regeneration in Drosophila

    Salvador C Herrera, Ginés Morata
    The reconstruction of damaged structures during regeneration requires cell reprogramming mediated by the up regulation of the JNK pathway and the transient debilitation of the epigenetic control mechanism.
    1. Stem Cells and Regenerative Medicine

    Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria

    Carolyn E Adler, Chris W Seidel ... Alejandro Sánchez Alvarado
    A chemical method has been developed for studying single organ regeneration and fate specification of stem cells in an adult organism.