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    1. Immunology and Inflammation

    Thymic self-recognition-mediated TCR signal strength modulates antigen- specific CD8+ T cell pathogenicity in non-obese diabetic mice

    Chia-Lo Ho, Li-Tzu Yeh ... Huey-Kang Sytwu
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology
    2. Neuroscience

    Voltage imaging reveals the emergence of population activity in the spinal cord

    Asuka Shiraishi, Ayane Hayashi ... Sachiko Tsuda
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Maximized field-of-view deep-brain calcium imaging through gradient-index lenses

    Chenmao Wang, Zongyue Cheng ... Meng Cui
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Brain Perfusion Imaging of a Large Population: Arterial Spin Labelling MRI in UK Biobank

    Thomas W Okell, Xinyi Xu ... Michael A Chappell
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Microbiology and Infectious Disease

    Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis

    Kamal L Nahas, Viv Connor ... Colin M Crump
    Deletion of specific herpes simplex virus proteins prevents the progression of virus assembly at discrete stages, allowing detailed 3D imaging of rare events in the morphogenesis of virus particles.
    1. Evolutionary Biology
    2. Genetics and Genomics

    G-protein-coupled receptor diversity and evolution in the closest living relatives of metazoa

    Alain Garcia De Las Bayonas, Nicole King
    Up-to-date computational pipeline characterizes G-protein-coupled receptor (GPCR) repertoires in the closest relatives of metazoans, providing a framework to investigate the evolutionary origins and ancestral functions of key metazoan signaling pathways.
    1. Biochemistry and Chemical Biology

    A green lifetime biosensor for calcium that remains bright over its full dynamic range

    Franka H van der Linden, Stephen C Thornquist ... Joachim Goedhart
    Directed evolution was used to engineer a green fluorescent biosensor for quantitative calcium imaging that remains fluorescent, yet shows a large change in lifetime in cells.
    1. Neuroscience

    PRRT2 as an auxiliary regulator of Nav channel slow inactivation

    Bin Lu, Qi-Wu Xu ... Zhi-Qi Xiong
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Microbiology and Infectious Disease

    Membrane affinity difference between MinD monomer and dimer is not crucial for MinD gradient formation in Bacillus subtilis

    Laura C Bohorquez, Henrik Strahl ... Leendert W Hamoen
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling
    1. Neuroscience

    Movie reconstruction from mouse visual cortex activity

    Joel Bauer, Troy W Margrie, Claudia Clopath
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
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