Browse our latest research

Page 21 of 1,800
    1. Neuroscience

    Dissecting surveying behavior of reactive microglia under chronic neurodegeneration

    Sunitha Subhramanian, Olga Bocharova ... Ilia V Baskakov
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    Deep Learning Reveals Endogenous Sterols as Allosteric Modulators of the GPCR-Gα Interface

    Sanjay Kumar Mohanty, Aayushi Mittal ... Gaurav Ahuja
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Evolutionary Biology

    Fluidity and Predictability of Epistasis on an Intragenic Fitness Landscape

    Sarvesh Baheti, Namratha Raj, Supreet Saini
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Predictive modeling of hematoma expansion from non-contrast computed tomography in spontaneous intracerebral hemorrhage patients

    Natasha Ironside, Kareem El Naamani ... ERICH Investigators and the VISTA-ICH collaboration
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Structural Biology and Molecular Biophysics

    Cryo-EM Reveals Regulatory Mechanisms Governing Substrate Selection and Activation of Human LONP1

    Jeffrey T Mindrebo, Lauren Alexandrescu ... Gabriel C Lander
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    DendroTweaks: An interactive approach for unraveling dendritic dynamics

    Roman Makarov, Spyridon Chavlis, Panayiota Poirazi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Plant Biology

    Companion cells with high florigen production express other small proteins and reveal a nitrogen-sensitive FT repressor

    Hiroshi Takagi, Shogo Ito ... Takato Imaizumi
    A distinct subset of leaf companion cells expresses high levels of the florigen gene, and the same cells also produce other possible mobile floral regulators and small proteins.
    1. Computational and Systems Biology

    OpenSpliceAI provides an efficient modular implementation of SpliceAI enabling easy retraining across nonhuman species

    Kuan-Hao Chao, Alan Mao ... Mihaela Pertea
    OpenSpliceAI is an open, retrainable framework for splice site prediction that enables rapid, memory-efficient, cross-species analyses at scale with accuracy comparable to SpliceAI.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Dissociation of the nuclear basket triggers chromosome loss in aging yeast

    Mihailo Mirkovic, Jordan McCarthy ... Yves Barral
    Aging results in remodeling of the nuclear pore complex and leakage of intron-containing pre-mRNA out of the nucleus, altering gene function and mitotic stability of old cells.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Endogenous FGFs drive ERK-dependent cell fate patterning in 2D human gastruloids

    Kyoung Jo, Zong-Yuan Liu ... Idse Heemskerk
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling