Browse our latest research

Page 5 of 1,809
    1. Medicine
    2. Computational and Systems Biology

    Global molecular landscape of early MASLD progression in obesity

    Qing Zhao, William De Nardo ... Philipp Kaldis
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Epidemiology and Global Health

    Subnational tailoring of ITN distributions to maximise malaria control

    Andrew C Glover, Hannah Koenker ... Thomas S Churcher
    Not revised
    Reviewed Preprint v1
    • Useful
    • Convincing
    1. Genetics and Genomics

    Competition for the conserved branch point sequence influences physiological outcomes in pre-mRNA splicing

    Karen Larissa Pereira de Castro, Jose M Abril ... W Samuel Fagg
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Local Inhibitory Dynamics Underpin Temporal Integration and Functional Segregation between Barrels and Septa in the Mouse Barrel Cortex

    Ali Özgür Argunşah, Tevye Jason Stachniak ... Theofanis Karayannis
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Affinity-guided labeling reveals P2X7 nanoscale membrane redistribution during BV2 microglial activation

    Benoit Arnould, Adeline Martz ... Thomas Grutter
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Functionally-Coupled Ion Channels Begin Co-assembling at the Start of Their Synthesis

    Roya Pournejati, Jessica M Huang ... Oscar Vivas
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Immunology and Inflammation
    2. Stem Cells and Regenerative Medicine

    IL-27 limits HSPC differentiation during infection and protects from stem cell exhaustion

    Daniel L Aldridge, Zachary Lanzar ... Christopher A Hunter
    Functional analyses showcase that in the absence of IL-27, hematopoietic stem and progenitor cells are more likely to become monocytes during toxoplasmosis, making them less responsive after infection.
    1. Neuroscience

    Early changes in the properties of CA3 engram cells explored with a novel viral tool in mice

    Dario Cupolillo, Noelle Grosjean ... Christophe Mulle
    A novel viral tool (FLEN) is designed, and used to monitor changes in the intrinsic and synaptic properties of engram cells quickly (3–6 hours) following encoding of a memory.
    1. Genetics and Genomics

    Chromatin accessibility variation provides insights into missing regulation underlying immune-mediated diseases

    Raehoon Jeong, Martha L Bulyk
    Analyzing population-level chromatin accessibility data shows added benefit over utilizing only gene expression data in elucidating the genetic mechanism of disease-associated variants.
    1. Neuroscience

    Dissociable memory modulation mechanisms facilitate fear amnesia at different timescales

    Yinmei Ni, Ye Wang ... Jian Li
    The retrieval-extinction paradigm elicits a short-term fear amnesia that differs in cue specificity, timescale, and dependence on thought-control ability from the long-term amnesia believed to be associated with memory reconsolidation.