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    1. Microbiology and Infectious Disease

    Global transcription factors analyses reveal hierarchy and synergism of regulatory networks and master virulence regulators in Pseudomonas aeruginosa

    Jiadai Huang, Yue Sun ... Xin Deng
    Systematic ChIP-seq profiling of 172 transcription factors in Pseudomonas aeruginosa reveals a hierarchical regulatory architecture governing virulence and establishes a searchable database to guide antimicrobial drug discovery.
    1. Neuroscience
    2. Computational and Systems Biology

    Long-range neural pathways for octopus chemotactile processing revealed from periphery-to-brain by centimeter-field microCT

    Andrew Sugarman, Daniel Vanselow ... Keith C Cheng
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    Molidustat Targets a Synthetic Lethal Vulnerability in APC-Mutant Colorectal Cancer through GSTP1 and PHD2 Co-Inhibition

    Chiara Asselborn, Agata N Makar ... Alexander von Kriegsheim
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Audiovisual congruency drives confidence in presence and absence

    Perrine Porte, Matan Mazor ... Louise Goupil
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Microbiology and Infectious Disease

    Five-layer systems analysis of Leishmania stage differentiation reveals an essential role for protein degradation in parasite development

    Pascale Pescher, Thibaut Douché ... Gerald F Späth
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Cross-Species BAC Transgenesis Reveals Long-Range Regulation Drives Variation in Brain Oxytocin Receptor Expression and Social Behaviors

    Mina Tsukamoto, Luis AE Nagai ... Qi Zhang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Ecology

    Developmental constraints mediate the reversal of temperature effects on the autumn phenology of European beech after the summer solstice

    Dominic Rebindaine, Thomas W Crowther ... Constantin M Zohner
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Ecology

    The overall and sequence-specific degradation of soil extracellular 16S rRNA genes across China: rates and influential factors

    Ting Li, Song Zhang ... Rongxiao Che
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Immunology and Inflammation

    Gelsolin Counteracts ER Stress-Driven Inflammatory Circuits in Psoriasis-like Dermatitis

    Daisuke Ori, Haruna Okude ... Taro Kawai
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience
    2. Computational and Systems Biology

    Gene specificity landscapes for comparative transcriptomic analysis across tissues, cell types, and species

    Erik Bot, Jose Davila-Velderrain
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
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