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Page 5 of 1,842
    1. Chromosomes and Gene Expression
    2. Microbiology and Infectious Disease

    Epigenetics and chromatin structure regulate var2csa expression and the placental-binding phenotype in Plasmodium falciparum

    Todd Lenz, Madle Sirel ... Ulf Ribacke
    Placenta-binding parasites show that chromatin-based mechanisms regulate placental malaria virulence gene, var2csa, and requires loss of H3K9me3-mediated heterochromatic silencing and 3D nuclear repositioning away from telomeric-repressive clusters.
    1. Developmental Biology

    Heterogeneity of Sonic Hedgehog response dynamics and fate specification in single neural progenitors

    Fengzhu Xiong, Andrea R Tentner ... Sean G Tsung-Megason
    Comparing signaling response profiles and fate outcomes in single cells reveals logic and limits of signal interpretation.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    A lipoprotein partner for the Escherichia coli outer membrane protein TolC

    Jim Horne, Elise Kaplan ... Ben F Luisi
    Structural and biochemical analyses identify a bacterial lipoprotein that associates with the outer membrane component of tripartite multi-drug efflux pumps, and its potential functional roles are explored by complementary bioinformatics, proteomcid and genetic approaches.
    1. Neuroscience

    BlueBerry: Closed-loop wireless optogenetic manipulation in freely moving animals

    Ali Nourizonoz, Benoit Girard ... Daniel Huber
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Functional imaging of nine distinct neuronal populations under a miniscope in freely behaving animals

    Mary L Phillips, Nicolai T Urban ... Ryohei Yasuda
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    MIRO1 controls energy production and proliferation of vascular smooth muscle cells

    Lan Qian, Olha M Koval ... Isabella M Grumbach
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Dopaminergic Modulation of Mushroom Body Output Neurons Mediates Nociception-Induced Escape in Drosophila

    Chi-Lien Yang, Chia-Wen Chen ... Ann-Shyn Chiang
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Computational and Systems Biology

    Thymic selection of the T cell receptor repertoire is biased toward autoimmunity in females

    Hélène Vantomme, Valentin Quiniou ... David Klatzmann
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
    1. Neuroscience

    Spontaneous emergence and evolution of neuronal sequences in recurrent networks

    Shuai Shao, Juan Luis Riquelme, Julijana Gjorgjieva
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Increased layer 5 Martinotti cell excitation reduces pyramidal cell population plasticity and improves learned motor execution

    Thawann Malfatti, Anna Velica ... Klas Kullander
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
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