Browse our latest research

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    1. Neuroscience

    Multiple event segmentation mechanisms in the human brain

    Tan T Nguyen, Joset A Etzel ... Jeffrey M Zacks
    The brain uses separate prediction error and prediction uncertainty signals to trigger event boundaries.
    1. Genetics and Genomics

    Optimised genome editing for precise DNA insertion and substitution using prime editors in zebrafish

    Yosuke Ono, Martin Peterka ... Steffen Scholpp
    Nickase and nuclease Prime Editors offer complementary routes for precise zebrafish genome editing, balancing accuracy for substitutions with efficiency for short insertions.
    1. Biochemistry and Chemical Biology

    Profiling of terminating ribosomes reveals translational control at stop codons

    Longfei Jia, Yuanhui Mao ... Shu-Bing Qian
    Systematic characterization of terminating ribosomes uncovers sequence features influencing ribosome dynamics at stop codons with direct implications in 3' UTR translation.
    1. Neuroscience

    Development of auditory and spontaneous movement responses to music over the first postnatal year

    Trinh Nguyen, Félix Bigand ... Giacomo Novembre
    Although auditory encoding of music is robust early in infancy, the transformation of this input into movement patterns develops substantially over the first postnatal year, without reaching full maturity.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Pervasive relaxed selection on spermatogenesis genes coincident with the evolution of polygyny in gorillas

    Jacob D Bowman, Neide Silva ... Vincent J Lynch
    Genes associated with male reproductive biology appear to be under relaxed selective constraint in a primate species with low sperm competition.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Arrayed single-gene perturbations identify drivers of human anterior neural tube closure

    Roya E Huang, Giridhar M Anand ... Sharad Ramanathan
    A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure.
    1. Neuroscience

    Heritability of movie-evoked brain activity and connectivity

    David C Gruskin, Daniel J Vieira ... Gaurav H Patel
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Ecology

    Coordinated beak–tongue mechanics enable dexterous seed manipulation in songbirds

    Maja Mielke, Falk Mielke ... Sam Van Wassenbergh
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Noise in Competing Representations Determines the Direction of Memory Biases

    Andrey Chetverikov, Sabrina Hansmann-Roth
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Physics of Living Systems

    Sarcomere dynamic instability and stochastic heterogeneity drive robust cardiomyocyte contraction

    Daniel Haertter, Lara Hauke ... Christoph F Schmidt
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Compelling