Browse our latest research

Page 5 of 1,832
    1. Evolutionary Biology

    The population structure of invasive Lantana camara is shaped by its mating system

    P Praveen, Rajesh Gopal, Uma Ramakrishnan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Incomplete
    1. Developmental Biology

    Mouse germline cysts contain a fusome-like structure that mediates oocyte development

    Madhulika Pathak, Allan C Spradling
    Mammalian oocytes utilize a conserved combination of cell cycle control, cytoskeletal organization, and polarity pathways that are fundamentally shared with other vertebrates and invertebrates.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Cell type-specific network analysis in Diversity Outbred mice identifies genes potentially responsible for human bone mineral density GWAS associations

    Luke J Dillard, Gina Calabrese ... Charles Farber
    Single-cell transcriptomics data from mouse bone-relevant cells was used to inform human bone mineral density genome-wide association studies and prioritize genetic targets with potential causal roles in the development of osteoporosis.
    1. Developmental Biology
    2. Genetics and Genomics

    A genome-wide MAGIC kit for recombinase-independent mosaic analysis in Drosophila

    Yifan Shen, Ann T Yeung ... Chun Han
    A comprehensive toolkit enables genome-wide, recombinase-independent mosaic analysis in Drosophila, permitting clonal analysis of pericentromeric genes, deficiency chromosomes, and interspecific hybrids previously inaccessible to standard methods.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Multiple modes of cholesterol translocation in the human Smoothened receptor

    Prateek D Bansal, Maia Kinnebrew ... Diwakar Shukla
    Multiple competing hypotheses concerning the cholesterol accessibility of oncoprotein Smoothened are quantitatively assessed and experimentally validated, showing that cholesterol takes two pathways from either membrane leaflet to the binding sites.
    1. Neuroscience

    Boosting Hyperalignment Performance with Age-specific Templates

    Yuqi Zhang, Maria Ida Gobbini ... Ma Feilong
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    The effect of physical activity on brain structure and cognitive function in the population-based cohort of LIFE-Adult-Study

    Polona Kalc, Rober Dahnke ... Christian Gaser
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Evolutionary Biology

    Heterozygote advantage cannot explain MHC diversity, but MHC diversity can explain heterozygote advantage

    Joshua L Cherry
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Noradrenergic infraslow rhythm during sleep is the critical link between heart-rate dynamics and memory consolidation

    Sofie S Jacobsen, Allison B Morehouse ... Celia Kjaerby
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Epidemiology and Global Health

    Repurposed small molecule toxin inhibitors neutralise a diversity of venoms from the Neotropical viperid snake genus Bothrops

    Rachel H Clare, Adam Westhorpe ... Nicholas R Casewell
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid