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    1. Neuroscience

    Hierarchical priors enable neural prediction of perceived biological motion

    Ingmar EJ de Vries, Floris P de Lange, Moritz F Wurm
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Layer-specific spatiotemporal dynamics of feedforward and feedback in human visual object perception

    Tony Carricarte, Siying Xie ... Radoslaw M Cichy
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    • Solid
    1. Structural Biology and Molecular Biophysics

    In-cell cryo-electron tomography reveals differential effects of type I and type II kinase inhibitors on LRRK2 filament formation and microtubule association

    Tamar Basiashvili, Joshua Hutchings ... Elizabeth Villa
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Patient-specific midbrain organoids with CRISPR correction recapitulate neuronopathic Gaucher disease phenotypes and enable evaluation of novel therapies

    Yi Lin, Benjamin Liou ... Ying Sun
    Human midbrain organoids provide a foundation for the development of patient-specific preclinical models to support personalized therapeutic approaches and enable evaluation of disease mechanisms and therapeutic strategies in human context.
    1. Structural Biology and Molecular Biophysics

    Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling

    Nevin K Zacharia, Stefanie Kuhns ... Esben Lorentzen
    The IFT172 C-terminus bridges IFT-A and IFT-B complexes through mutually exclusive interactions with IFT140 and IFT144, and harbors a U-box-like domain linking intraflagellar transport to ubiquitin-dependent ciliary signaling.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    From multiplicity of infection to force of infection in sparsely sampled high-transmission Plasmodium falciparum populations

    Qi Zhan, Kathryn E Tiedje ... Mercedes Pascual
    Queuing theory links multiplicity of infection (MOI) to force of infection (FOI), enabling the estimation of transmission intensity for falciparum malaria (and other infectious diseases) from sparsely sampled surveys.
    1. Neuroscience

    Decoding spine nanostructure in cultured neurons derived from mouse models of mental disorder reveals a schizophrenia-linked role for Ecrg4

    Yutaro Kashiwagi, Qingrui Liu ... Shigeo Okabe
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Computational and Systems Biology

    TSvelo: Comprehensive RNA velocity by modeling the cascade of gene regulation, transcription and splicing

    Jiachen Li, Zhe Wang ... Ye Yuan
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Distinct involvements of the subthalamic nucleus subpopulations in reward-biased decision-making in monkeys

    Kathryn Branam, Joshua I Gold, Long Ding
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Apparent cooperativity between human CMV virions introduces errors in conventional methods of calculating multiplicity of infection

    Christopher Peterson, Joshua Miller ... Vitaly V Ganusov
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
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