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    1. Computational and Systems Biology
    2. Medicine

    Global molecular landscape of early MASLD progression in human obesity

    Qing Zhao, William De Nardo ... Philipp Kaldis
    GTPases could be drivers of liver fibrosis in MASLD and potential future therapeutic targets.
    1. Neuroscience

    Alcohol attenuates CRF-induced excitatory effects from the extended amygdala to dorsostriatal cholinergic interneurons

    Amanda Essoh, Xueyi Xie ... Jun Wang
    Stress-related corticotropin-releasing factor signaling directly modulates striatal cholinergic circuits, and alcohol exposure disrupts this control, revealing a circuit mechanism linking stress, alcohol use, and impaired behavioral flexibility.
    1. Microbiology and Infectious Disease

    Bivalent mRNA booster encoding virus-like particles elicits potent polyclass receptor-binding domain antibodies in pre-vaccinated mice

    Chengcheng Fan, Alexander A Cohen ... Magnus AG Hoffmann
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Convincing
    1. Cell Biology
    2. Medicine

    Uncovering Shared and Tissue-Specific Molecular Adaptations to Intermittent Fasting in Liver, Brain, and Muscle

    Yibo Fan, Senuri De Silva ... Thiruma V Arumugam
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Inhibitory columnar feedback neurons are involved in motion processing in Drosophila

    Miriam Henning, Madhura Ketkar ... Marion Silies
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Computational and Systems Biology
    2. Cancer Biology

    Systematic Analysis of Network-driven Adaptive Resistance to CDK4/6 and Estrogen Receptor Inhibition using Meta-Dynamic Network Modelling

    Anthony Hart, Sung-Young Shin, Lan K Nguyen
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Neuroscience

    Early Sleep-Dependent Sensory Gating in the Olfactory System

    Diego Serantes, Diego Gallo ... Matías Cavelli
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    A stress-activated neuronal ensemble in the supramammillary nucleus produces anxiety-like behavior in male mice

    Jinming Zhang, Kexin Yu ... Jing Han
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cancer Biology

    Turning aging cells into a live vaccine: engineered senescent cancer cells with adjuvant celecoxib for immunotherapy

    Yuewei Wang, Ante Ou ... Yongzhuo Huang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Structural Biology and Molecular Biophysics

    A Structural Code for Assembly Specificity in GID/CTLH-Type E3 Ligases

    Pia Maria van gen Hassend, Hermann Schindelin
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
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