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    1. Physics of Living Systems

    Cell strain-stiffening drives cell breakout from embedded spheroids

    Shabeeb Ameen, Kyungeun Kim ... Tao Zhang
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics
    2. Neuroscience

    Dominant α-tubulin mutations rescue tauopathy neurodegenerative phenotypes in C. elegans

    Sarah J Benbow, Aleen D Saxton ... Brian C Kraemer
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Cognitive control networks in human and macaque

    Valentina Mione, Freja Holm Prins ... John Duncan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology

    Proteolytic remodeling by Yme1 enables mitochondrial-derived compartment formation

    Sai Sangeetha Balasubramaniam, Amy E Curtis ... Adam L Hughes
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Hierarchical priors enable neural prediction of perceived biological motion

    Ingmar EJ de Vries, Floris P de Lange, Moritz F Wurm
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Physics of Living Systems
    2. Evolutionary Biology

    Ecological diversification in rapidly evolving populations

    Daniel PGH Wong, Benjamin H Good
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Layer-specific spatiotemporal dynamics of feedforward and feedback in human visual object perception

    Tony Carricarte, Siying Xie ... Radoslaw M Cichy
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    • Solid
    1. Structural Biology and Molecular Biophysics

    Intraflagellar transport protein IFT172 contains a C-terminal ubiquitin-binding U-box-like domain involved in ciliary signaling

    Nevin K Zacharia, Stefanie Kuhns ... Esben Lorentzen
    The IFT172 C-terminus bridges IFT-A and IFT-B complexes through mutually exclusive interactions with IFT140 and IFT144, and harbors a U-box-like domain linking intraflagellar transport to ubiquitin-dependent ciliary signaling.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    Patient-specific midbrain organoids with CRISPR correction recapitulate neuronopathic Gaucher disease phenotypes and enable evaluation of novel therapies

    Yi Lin, Benjamin Liou ... Ying Sun
    Human midbrain organoids provide a foundation for the development of patient-specific preclinical models to support personalized therapeutic approaches and enable evaluation of disease mechanisms and therapeutic strategies in human context.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    From multiplicity of infection to force of infection in sparsely sampled high-transmission Plasmodium falciparum populations

    Qi Zhan, Kathryn E Tiedje ... Mercedes Pascual
    Queuing theory links multiplicity of infection (MOI) to force of infection (FOI), enabling the estimation of transmission intensity for falciparum malaria (and other infectious diseases) from sparsely sampled surveys.
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