Sébastien Jeay
Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Sébastien Jeay, Employee of Novartis Institutes for BioMedical Research.
Swann Gaulis
Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Swann Gaulis, Employee of Novartis Institutes for BioMedical Research.
Stéphane Ferretti
Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Stéphane Ferretti, Employee of Novartis Institutes for BioMedical Research.
Hans Bitter
Disease Area Oncology, Novartis Institutes for BioMedical Research, Cambridge, United States
Competing interests
Hans Bitter, Employee of Novartis Institutes for BioMedical Research.
Moriko Ito
Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Moriko Ito, Employee of Novartis Institutes for BioMedical Research.
Thérèse Valat
Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Thérèse Valat, Employee of Novartis Institutes for BioMedical Research.
Masato Murakami
Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Masato Murakami, Employee of Novartis Institutes for BioMedical Research.
Stephan Ruetz
Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Stephan Ruetz, Employee of Novartis Institutes for BioMedical Research.
Daniel A Guthy
Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Daniel A Guthy, Employee of Novartis Institutes for BioMedical Research.
Caroline Rynn
Metabolism and Pharmacokinetics, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Caroline Rynn, Employee of Novartis Institutes for BioMedical Research.
Michael R Jensen
Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Michael R Jensen, Employee of Novartis Institutes for BioMedical Research.
Marion Wiesmann
Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Marion Wiesmann, Employee of Novartis Institutes for BioMedical Research.
Joerg Kallen
Center of Proteomic Chemistry, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Joerg Kallen, Employee of Novartis Institutes for BioMedical Research.
Pascal Furet
Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Pascal Furet, Employee of Novartis Institutes for BioMedical Research.
François Gessier
Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
François Gessier, Employee of Novartis Institutes for BioMedical Research.
Philipp Holzer
Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Philipp Holzer, Employee of Novartis Institutes for BioMedical Research.
Keiichi Masuya
Peptidream Inc, Tokyo, Japan
Competing interests
Keiichi Masuya, was an employee of Novartis Institutes for BioMedical Research and is now an employee of Peptidream Inc. and has ownership interest (including patents) in Peptidream Inc.
Jens Würthner
Translational Clinical Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Jens Würthner, Employee of Novartis Institutes for BioMedical Research.
Ensar Halilovic
Translational Clinical Oncology, Novartis Institutes for BioMedical Research, Cambridge, United States
Competing interests
Ensar Halilovic, Employee of Novartis Institutes for BioMedical Research.
Francesco Hofmann
Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Francesco Hofmann, Employee of Novartis Institutes for BioMedical Research.
William R Sellers
Disease Area Oncology, Novartis Institutes for BioMedical Research, Cambridge, United States
Competing interests
William R Sellers, Employee of Novartis Institutes for BioMedical Research. Holds the position of VP/Global Head of Oncology in Novartis Institutes for BioMedical Research and has ownership interest (including patents) in Novartis Pharmaceuticals.
Diana Graus Porta
Disease Area Oncology, Novartis Institutes for BioMedical Research, Basel, Switzerland
Competing interests
Diana Graus Porta, Employee of Novartis Institutes for BioMedical Research.
Animal experimentation: All animal studies were conducted in accordance to procedures covered by permit number 1975 issued by the Kantonales Veterinäramt Basel-Stadt and strictly adhered to the Eidgenössisches Tierschutzgesetz and the Eidgenössische Tierschutzverordnung. All animals were allowed to adapt for 4 days and housed in a pathogen-controlled environment (5 mice/Type III cage) with access to food and water ad libitum and were identified with transponders.
© 2015, Jeay et al.
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