1. Developmental Biology
  2. Evolutionary Biology
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Developmental Variability: Exerting an influence on evolution

  1. Charles C Roseman  Is a corresponding author
  1. University of Illinois, Urbana-Champaign, United States
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Cite this article as: eLife 2020;9:e55952 doi: 10.7554/eLife.55952
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Differences in the developmental trajectories of two strains of mice result in different degrees of phenotypic variation.

(A) The upper first molar is longer in DUHi mice (blue line) than in FVB mice (red line); the variance in the length is also higher in the DUHi mice. (B) This difference in variance arises from the fact that the developmental trajectory of the DUHi mouse (curved blue line) occupies more of the developmental space (solid blue line along the x-axis) in any interval of time (defined by the dashed black lines) than in the FVB mice (solid red line). Mouse skull image provided by Benedikt Hallgrímsson and Rebecca Green.

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