1. Developmental Biology
Download icon

Fertilization: Conserved sperm factors are no longer a bone of contention

  1. Xue Mei
  2. Andrew Singson  Is a corresponding author
  1. Waksman Institute of Microbiology and Department of Genetics, Rutgers University, United States
Insight
Cite this article as: eLife 2021;10:e68976 doi: 10.7554/eLife.68976
1 figure

Figures

The interruption of fertilization in Dcst-related gene mutants in different species.

(A) In mammals, sperm mutant for Dcst1 and/or Dcst2 can penetrate the egg coat and contact the egg plasma membrane, but they do not fuse with the egg. (B) In C. elegans, spe-42 or spe-49 mutant sperm can contact the egg plasma membrane, but they do not fuse with the egg. (C) In Drosophila, giant sperm enter the egg through a small opening called a micropyle: however, in snky mutant sperm the plasma membrane of the sperm does not break down, thus blocking nuclear fusion.

Download links

A two-part list of links to download the article, or parts of the article, in various formats.

Downloads (link to download the article as PDF)

Download citations (links to download the citations from this article in formats compatible with various reference manager tools)

Open citations (links to open the citations from this article in various online reference manager services)