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A text-mining study suggests that about half of the papers reporting the results of experiments on mice do not report the sex and age of the mice.

Peer review scores were poorly predictive of research project success in this large dataset, suggesting that reviewers cannot reliably predict which meritorious applications are most likely to be productive.

A EASAC working group on gain-of-function research has emphasised the importance of ensuring that the necessary safeguards and policies are in place.

The high rates of attrition that occur in drug development are widely regarded as problematic, but the failure of well-designed studies benefits both researchers and healthcare systems.

Journals should publish referee reports and respond to well-founded concerns about papers after publication.

Most scientists admit to their errors but, as Eve Marder explains, the scientific community as a whole needs to rethink the way it recognizes achievement.

Interviews with senior biomedical researchers reveal a perceived decline in trust in the scientific enterprise, in large part because the quantity of new data exceeds the field's ability to process it appropriately.

A citizen science game reveals play interest patterns that could inform crowdsourcing experiment design.

Science hackathons can help academics, particularly those in the early stage of their careers, to build collaborations and write research proposals.

Community nurturing is the single most important factor in determining the sustainability of an open source project such as BioJS.