Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
Inhibition of Nav1.7 sodium channels in human dorsal root ganglion neurons had larger effects to reduce threshold and upstroke velocity of action potentials compared to Nav1.8 inhibition but smaller effects to reduce repetitive firing of action potentials.
Alex Zilinskas, Amir Balakhmet ... Sarah A Stanley
Mycobacterium tuberculosis uses its type VII secretion system and surface lipid phthiocerol dimycocerosate to suppress protective host Th17 cell responses.
Representations from models that explicitly encode semantic roles (who did what to whom) align better with activity in language regions of the brain than representations from transformers do.
Vincent Richter, Tilman Triphan ... Andreas S Thum
Comprehensive ultrastructural reconstruction of the Drosophila larval pharyngeal sensory system reveals the organization and diversity of its sensory structures and enables future investigations into sensory processing, feeding decisions, and behavior.
Recording the spiking activity of muscle fibers at high resolution in awake, behaving mice, reveals that locomotor speed is driven by highly variable subsets of motor units.
Md Zubayer Hossain Saad, William G Ryan ... Bruce A Bamber
An odorant is encoded in the periphery as independent inputs of attractive and repulsive valence, which are then integrated and balanced to drive overall chemotactic behavior.
Naturally occurring bacterial endosymbionts can modify population growth, crop damage, and dispersal in the Russian wheat aphid, a major pest of cereal crops, highlighting their potential for sustainable pest management.
Marc E Normandin, Pedro M Ogallar ... Isabel A Muzzio
Stable and dynamic prelimbic neurons preserve threat-generalization gradients despite ensemble turnover, supporting enduring representations of stimulus significance rather than freezing.
