Joanna C Porter, Jamie Inshaw ... Venizelos Papayannopoulos
Nebulized dornase alfa endonuclease reduces inflammation, coagulopathy, and the length of hospitalization in individuals with severe COVID-19 pneumonia.
The intermediate region of the hippocampus is critical for strategic goal-directed navigation to the higher-value location, whereas the dorsal hippocampus implements the precise targeting of the goal location.
A lineage-based intersectional genetic approach reveals brain-wide distribution and input connectivity of axo-axonic interneuron cells and establishes experimental access to study the circuit function of a ground truth cell type.
ROH-DICE is an efficient method for detecting ROH clusters in biobank data, enabling the study of population history of large cohorts, and providing a new genome-wide association analysis approach for finding disease-causing loci with multi-marker recessive effects.
Cristina Sáenz de Miera, Nicole Bellefontaine ... Carol F Elias
Glutamate neurotransmission from hypothalamic ventral premammillary nucleus is indispensable for leptin action in pubertal development and typical reproduction.
Findings identify a new link between oncogenic ß-catenin and exosome biogenesis, which may serve as an important nodal point in the immune escape of hepatocellular carcinoma.
The modulatory neurochemicals acetylcholine and dopamine are released differentially into the basolateral amygdala depending on the emotional content of vocalizations and the sex, hormonal state, and experience of listening animals.
Richard Sejour, Janet Leatherwood ... Bruce Futcher
The 5' ends of genes are slightly enriched for rare codons largely because the ends turnover in evolution and gather rare codons, and these rare codons do not improve translation.
