Browse our Research Articles

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    1. Developmental Biology
    2. Genetics and Genomics

    Single-cell co-mapping reveals relationship between chromatin state and gene expression in early zebrafish development

    Vivek Bhardwaj, Alberto Griffa ... Alexander van Oudenaarden
    A robust and quantitative map links chromatin modification and gene expression of cells during zebrafish embryogenesis.
    1. Neuroscience

    Brain-wide mapping of layer-specific functional connectivity in the human cortex at 3T using draining-vein-suppressed fMRI

    Wei-Tang Chang, Weili Lin, Kelly S Giovanello
    A velocity-nulled 3T GE-EPI fMRI method enabling 0.9-mm whole-brain imaging that suppresses vascular contamination and reliably maps layer-specific functional connectivity in human cortex.
    1. Microbiology and Infectious Disease

    Antibiotic potentiation and inhibition of cross-resistance in pathogens associated with cystic fibrosis

    Nikol Kadeřábková, R Christopher D Furniss ... Despoina AI Mavridou
    Targeting disulfide bond formation disables multiple antibiotic resistance mechanisms and prevents cross-protection between pathogens associated with cystic fibrosis lung infections, restoring antibiotic efficacy in polymicrobial settings.
    1. Neuroscience

    Modeling the hallucinatory effects of classical psychedelics in terms of replay-dependent plasticity mechanisms

    Colin Bredenberg, Fabrice Normandin ... Guillaume Lajoie
    Computational simulations indicate that classical psychedelics could induce hallucinations by co-opting neural circuitry dedicated to sleep-dependent replay and consolidation, providing a theoretical link between seemingly disparate fields of inquiry.
    1. Neuroscience

    Alpha-band phase modulates perceptual sensitivity by changing internal noise and sensory tuning

    April Pilipenko, Alexandra McGowan, Jason Samaha
    Alpha-band, 8–13 Hz, neural oscillations phasically modulate the sensitivity of visual detection by changing internal sensory noise.
    1. Neuroscience

    Dimorphic neural network architecture prioritizes sexual-related behaviors in male Caenorhabditis elegans

    Xuebin Wang, Hanzhang Liu ... He Liu
    Graph theory and computational modeling reveal that neural network architecture biases the male Caenorhabditis elegans brain toward prioritized sexual behaviors.
    1. Neuroscience

    How individual vigor shapes human–human physical interaction

    Dorian Verdel, Bastien Berret, Etienne Burdet
    Interactions between pairs of humans lead to the emergence of a dyadic vigor with similar characteristics as individual vigor, where both partners adapt, with the slower having a critical role.
    1. Structural Biology and Molecular Biophysics

    Structural mechanisms of pump assembly and drug transport in the AcrAB–TolC efflux system

    Xiaofei Ge, Zhiwei Gu, Jiawei Wang
    High‑resolution cryo‑EM structures uncover YbjP as a novel lipoprotein that positions TolC and supports conformational changes in E. coli drug efflux pumps mediating antibiotic resistance.
    1. Neuroscience

    Modality-agnostic decoding of vision and language from fMRI

    Mitja Nikolaus, Milad Mozafari ... Rufin VanRullen
    Modality-agnostic decoders leverage modality-invariant representations in human subjects' brain activity to predict stimuli irrespective of their modality (image, text, mental imagery).
    1. Physics of Living Systems

    Fragmentation and aggregation of cyanobacterial colonies

    Yuri Z Sinzato, Robert Uittenbogaard ... Maziyar Jalaal
    Flow experiments show how the formation of cyanobacterial colonies is driven by cell division, aggregation, and fragmentation under different hydrodynamic conditions.