A biologically plausible reinforcement learning model that integrates associative memory and hippocampal remapping explains context-dependent flexible behavior, neural dynamics, and psychosis-related symptoms.
Adriana Quijada-Freire, César A Santiago ... Mario Mellado
HIV-1 remodels the spatial organization of its co-receptor, CXCR4, on T cell membranes, showing that viral entry requires receptor clustering rather than simple receptor binding.
Ryan T Maloney, Athena Q Ye ... Benjamin L de Bivort
Individual flies have idiosyncratic preferences that shift over their lifetime in a way that depends on genotype and may be adaptive to rapidly changing environmental pressures.
In a stylized regime-shift detection task, human fMRI evidence shows that under- and overreactions to change arise from dissociable contributions of the frontoparietal network and ventromedial prefrontal cortex.
Marion Brickwedde, Rupali Limachya ... Ali Mazaheri
Early visual alpha oscillations correlate on a trial-by-trial basis with steady-state responses at later stages of the processing stream, implying a role in signal enhancement and interareal communication.
Francisco Muñoz-Carvajal, Nicole Sanhueza ... Felipe A Court
Age-related epigenetic regulation of mitochondrial stress responses drives neuronal degeneration and sensory decline, highlighting mitochondrial resilience as a potential target to preserve brain function during aging.