Browse our Research Articles

Cryo-EM structures unexpectedly show that there are two binding sites for RAB5, with the VPS15 site being the most evolutionarily ancient site, which is essential for endocytic sorting.

A phosphorylation site on Hsp70 previously linked to pathogen activity functions endogenously in DNA damage responses and connects chaperone regulation to cell cycle control.

BRCA1/2 mutations rewire the lung adenocarcinoma microenvironment through distinct immune programs, with BRCA1-linked type I interferon signaling and CD8⁺ T activation contrasting BRCA2-linked MHC-II antigen presentation and CD4⁺ T differentiation.

Glycolytic activation directly drives Kupffer cell loss in early metabolic dysfunction-associated steatotic liver disease, highlighting a targetable metabolic vulnerability.

Inhibitory GABAergic feedback neurons tune direction-selective motion signals in Drosophila, sharpening behavioral responses to rapidly changing visual stimuli and expanding canonical feedforward models of visual motion computation.

Hearing impairment selectively disrupts neural tracking of speech at both short and long temporal scales during multi-speaker listening, while preserving intermediate linguistic processing.

A navigational model exploring social learning strategies differing in cognitive complexity in homing pigeons shows that simple averaging sufficiently explains collective route improvements, without requiring cumulative cultural evolution.

Descending neurons that encode widefield motion vision in the fly have sexually dimorphic velocity tuning, while the wing beat amplitude, which these neurons presumably control, is monomorphic.

Early enhancer logic precisely aligns developmental boundaries by integrating HOX, GATA, and signaling inputs, ensuring correct tissue patterning and preventing mirror-image duplications in the developing wing.

High-level partner representations tune low-level visuomotor reflexes.