Browse our Research Articles

Page 2 of 1,485
    1. Neuroscience

    Involuntary feedback responses reflect a representation of partner actions

    Seth R Sullivan, John H Buggeln ... Joshua GA Cashaback
    High-level partner representations tune low-level visuomotor reflexes.
    1. Neuroscience

    The nucleus accumbens shell regulates hedonic feeding via a rostral hotspot

    Alina-Măriuca Marinescu, Eshita Kamal ... Marie A Labouesse
    Within the nucleus accumbens shell, a spatially defined rostral subregion selectively modulates hedonic feeding, revealing functional heterogeneity in reward circuitry underlying food consumption.
    1. Immunology and Inflammation

    Lipopolysaccharide stimulates dynamic changes in B cell metabolism to promote proliferation

    Dana MS Cheung, Momchil Razsolkov ... J Simon C Arthur
    B cell activation and antibody class switching requires coordinated metabolic rewiring, with essential roles for amino acid transport, cholesterol metabolism, and prenylation in driving proliferation across multiple activating stimuli.
    1. Developmental Biology

    Single-cell transcriptomics-informed induced pluripotent stem cells differentiation to tenogenic lineage

    Angela Papalamprou, Victoria Yu ... Dmitriy Sheyn
    Exploring the differentiation of iPSC to trunk tenocytes and how the single-cell RNA sequencing and pathway analysis can assist in making it more specific.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    MORC2 mediates transcriptional regulation through liquid-liquid phase separation

    Yanshen Zhang, Weiya Xu ... Yihui Bi
    The dynamic internal fluidity of nuclear MORC2 condensates, rather than their mere assembly, is strictly required for transcriptional regulation and is selectively disrupted by neuropathy-linked mutations.
    1. Neuroscience

    Uncovering the electrical synapse proteome in retinal neurons via in vivo proximity labeling

    Stephan Tetenborg, Eyad Shihabeddin ... John O'Brien
    A proximity labeling screen uncovers the proteome of electrical synapses in retinal neurons.
    1. Neuroscience

    Multimodal MRI marker of cognition explains the association between cognition and mental health in the UK Biobank

    Irina Buianova, Mateus Silvestrin ... Narun Pat
    Multimodal stacking of MRI‑based markers of cognition reveals a shared brain architecture that links cognitive performance with mental health, explaining nearly half of their observed association.
    1. Cell Biology

    The multifaceted role of EXOC6A in ciliogenesis

    Te-Lin Lin, Chien-Ting Wu, Tang K Tang
    EXOC6A cooperates with myosin-Va to regulate vesicle trafficking and membrane remodeling during ciliogenesis, enabling ciliary vesicle maturation, transition zone assembly, and proper delivery of ciliary membrane proteins.
    1. Structural Biology and Molecular Biophysics

    Twelve phosphomimetic mutations induce the assembly of recombinant full-length human tau into paired helical filaments

    Sofia Lövestam, Jane L Wagstaff ... Sjors HW Scheres
    Phosphomimetic mutations allow the assembly of full-length recombinant tau into Alzheimer's paired helical filaments by disrupting intramolecular contacts between its ordered core and fuzzy coat.
    1. Cell Biology

    Cell surface localisation of GPI-anchored receptors in Trypanosoma brucei

    Sourav Banerjee, Nicola Minshall ... Mark Carrington
    The glycosylphosphatidylinositol (GPI)-anchored receptors in Trypanosoma brucei are not confined to the flagellar pocket but instead localise across the whole cell surface, reshaping our understanding of host immune evasion and nutrient uptake.