Browse our Research Articles

In a mouse model of E. coli meningitis, non-myeloid TLR4 signaling is a key determinant of the inflammatory response in all leptomeningeal cells and of the increase in vascular permeability.

Latent developmental potential facilitates trait re-evolution with novel phenotypic patterns, adding a new perspective to understanding of the origins of novel traits in evolutionary and developmental biology.

Threat, reward, and social hierarchy jointly shape innate defensive decisions through vigilance-dependent value integration.

Elfn1-mediated synaptic facilitation onto somatostatin-positive interneurons drives the local lateral inhibition required to functionally segregate cortical barrel and septal processing domains in mice.

Label-free optical imaging provides a direct readout of relaxed myosin conformational states in skeletal and cardiac muscle.

A three-layered modular architecture unifies diverse computational models of Drosophila larval behavior, enabling realistic closed-loop simulations from locomotion through chemotaxis to associative learning.

Cryo-electron microscopy structure of human G-protein-coupled receptor 30 in the presence of bicarbonate ions revealed unique extracellular pockets and critical residues for bicarbonate binding and activation.

Sibling-derived chimerism in marmosets is found only in cells of hematopoietic origin, especially microglia and macrophages in the brain, whose proportions vary widely across individuals and brain regions.

Epigenomics and quantitative imaging are used to investigate the re-establishment of histone modifications associated with the Polycomb group of epigenetic regulators during the Drosophila maternal-to-zygotic transition.

Parkinson’s disease-linked Pink1 loss disrupts protective glial support, and targeting glial vesicle trafficking preserves dopaminergic synapses.