Browse our Research Articles

Inhibiting PRMT1 and PRMT5 renders HR-proficient ovarian and breast cancers highly vulnerable to PARP inhibition by suppressing BRCAness and amplifying DNA-damage-driven innate immune signaling.

A flexible but automatic stimulus-response mapping mechanism complements forward model recalibration in walking adaptation, immediately accounting for perceived changes in the environment through perception altered by the same recalibration process.

Single-cell profiling reveals CD55+CD248+ tendon stem/progenitor cells.

The acquisition and expression of Pavlovian conditioned responding are shown to be lawfully related to objectively specifiable temporal properties of the events the animal is learning about.

HLA-DRA intronic haplotype associates with opposite effects on type 1 diabetes and celiac disease, refining genetic risk prediction and implicating complement genes C4A and C4B in divergent autoimmune pathways.

Disrupting left superior frontal sulcus selectively impaired perceptual but not value-based decisions, revealing segregated prefrontal circuits for integrating sensory evidence versus subjective preferences in human choice behaviour.

Cautious action timing under threat depends on glutamatergic signaling from the subthalamic nucleus to the midbrain, revealing a circuit mechanism for adaptive goal-directed behavior.

Facial emotion representations expand from sensory cortex to prefrontal regions across development, suggesting that the prefrontal cortex matures with development to enable a full understanding of facial emotion.

The carboxyl-terminal alanine-threonine-tailed protein ATP5α helps glioblastoma mitochondria maintain a high membrane potential and keep the permeability transition pore closed, thereby promoting tumor growth and increasing resistance to apoptosis.

Fluid flow analysis reveals that both swimming and sessile ciliates achieve competitive nutrient uptake, resolving the long-standing debate over the hydrodynamic advantage of either strategy.