Browse our Research Articles

Page 2 of 1,465
    1. Neuroscience

    High-fidelity neural speech reconstruction through an efficient acoustic-linguistic dual-pathway framework

    Jiawei Li, Chunxu Guo ... Yuanning Li
    Concurrent decoding of acoustic detail and linguistic structure enables natural, intelligible speech synthesis from limited human cortical recordings, resolving a fundamental constraint in neural speech reconstruction.
    1. Biochemistry and Chemical Biology

    Concatenated modular BK channel constructs reveal divergent stoichiometry in gating control by LRRC26 (γ1), pore, and selectivity filter

    Guanxing Chen, Qin Li ... Jiusheng Yan
    Regulatory stoichiometry in large-conductance potassium (BK) channels diverges by mechanism, separating single-subunit activation, graded pore contributions, and collective selectivity-filter control.
    1. Neuroscience

    Adjoint propagation of error signal through modular recurrent neural networks for biologically plausible learning

    Zhuo Liu, Hao Shu ... Tao Chen
    The adjoint propagation framework enables the concurrent flow of signals and errors, providing a biologically and physically plausible learning mechanism.
    1. Chromosomes and Gene Expression

    Acetylation of H3K115 is associated with fragile nucleosomes at CpG island promoters and active regulatory sites

    Yatendra Kumar, Dipta Sengupta ... Wendy A Bickmore
    Acetylation of histone H3 at the nucleosome surface is associated with destabilised nucleosomes and is a useful new functional genomics mark for identifying regulatory regions of the mammalian genome.
    1. Cell Biology

    SLC4A1 mutations that cause distal renal tubular acidosis alter cytoplasmic pH and cellular autophagy

    Grace Essuman, Midhat Rizvi ... Emmanuelle Cordat
    Distal renal tubular acidosis induced by some SLC4A1 variants is characterized by cytosolic pH alkalization, reduced ATP synthesis and defective autophagy degradative flux.
    1. Computational and Systems Biology

    Deep learning linking mechanistic models to single-cell transcriptomics data reveals transcriptional bursting in response to DNA damage

    Zhiwei Huang, Songhao Luo ... Jiajun Zhang
    DNA damage reshapes genome-wide transcriptional bursting, with distinct burst size and frequency programs associated with differentiation, apoptosis, and survival decisions.
    1. Medicine

    Sperm motility in mice with oligo-astheno-teratozoospermia restored by in vivo injection and electroporation of naked mRNA

    Charline Vilpreux, Paul Fourquin ... Jessica Escoffier
    Naked mRNA administration in the testes rescues sperm function, demonstrating a potential therapeutic approach for genetic male infertility.
    1. Evolutionary Biology
    2. Neuroscience

    Toward neuroanatomical and cognitive foundations of macaque social tolerance grades

    Sarah Silvere, Julien Lamy ... Sebastien Ballesta
    Macaque’s social tolerance grades, through its underlying cognitive demands, shape subcortical structures volumes.
    1. Neuroscience

    Dissociable dynamic effects of expectation during statistical learning

    Hannah H McDermott, Federico de Martino ... Ryszard Auksztulewicz
    Neural responses during statistical learning reveal dissociable dynamic effects of expectation, supporting the opposing process theory within trials while demonstrating contrasting effects across trials.
    1. Computational and Systems Biology
    2. Ecology

    Agent-based modeling reveals how bats navigate dense group emergences

    Omer Mazar, Yossi Yovel
    Acoustic jamming during bat emergence is weaker than expected because signal redundancy, echo integration, and simple movement rules enable robust navigation, as demonstrated by an agent‑based sensory-motor model.