Browse our Research Articles

Page 2 of 1,458
    1. Neuroscience

    A forebrain hub for cautious actions via the midbrain

    Ji Zhou, Muhammad Sarmad Sajid ... Manuel A Castro-Alamancos
    Cautious action timing under threat depends on glutamatergic signaling from the subthalamic nucleus to the midbrain, revealing a circuit mechanism for adaptive goal-directed behavior.
    1. Immunology and Inflammation

    Single-cell transcriptomics identifies altered neutrophil dynamics and accentuated T-cell cytotoxicity in tobacco-flavored e-cigarette-exposed mouse lungs

    Gagandeep Kaur, Thomas Lamb ... Irfan Rahman
    Profiling cell-specific immune responses reveals altered neutrophil function and enhanced T-cell mediated cell death following acute in vivo exposure to tobacco-flavored e-cigarette aerosol using single-cell technology.
    1. Neuroscience

    Human brain dynamics and spatiotemporal trajectories during threat processing

    Joyneel Misra, Luiz Pessoa
    Intrinsic neural attractors and extrinsic environmental inputs jointly steer the dynamic trajectories of brain activity during threat processing.
    1. Cancer Biology
    2. Cell Biology

    Mitochondrial protein carboxyl-terminal alanine-threonine tailing promotes human glioblastoma growth by regulating mitochondrial function

    Bei Zhang, Ting Cai ... Zhihao Wu
    The carboxyl-terminal alanine-threonine-tailed protein ATP5α helps glioblastoma mitochondria maintain a high membrane potential and keep the permeability transition pore closed, thereby promoting tumor growth and increasing resistance to apoptosis.
    1. Physics of Living Systems

    Feeding rates in sessile versus motile ciliates are hydrodynamically equivalent

    Jingyi Liu, Yi Man ... Eva Kanso
    Fluid flow analysis reveals that both swimming and sessile ciliates achieve competitive nutrient uptake, resolving the long-standing debate over the hydrodynamic advantage of either strategy.
    1. Evolutionary Biology

    Accelerated evolution in networked metapopulations of Pseudomonas aeruginosa

    Partha Pratim Chakraborty, Rees Kassen
    Centralized migration accelerates adaptation and drives parallel evolution, emphasizing the key influence of spatial organization on evolutionary dynamics across systems from pathogen transmission to species range shifts.
    1. Neuroscience

    Executive resources shape the impact of language predictability across the adult lifespan

    Merle Marie Schuckart, Sandra Martin ... Jonas Obleser
    Analyses of self-paced reading times reveal that linguistic prediction deteriorates under limited executive resources, with this resource sensitivity becoming markedly more pronounced with advancing age.
    1. Neuroscience

    Identifying regulators of associative learning using a protein-labelling approach in Caenorhabditis elegans

    Aelon Rahmani, Anna McMillen ... Yee Lian Chew
    An innovative and scalable proximity labelling method profiled proteins present in the Caenorhabditis elegans brain during learning, identifying known regulators as well as novel biological pathways.
    1. Structural Biology and Molecular Biophysics

    Cryo-EM structure revealed a novel F-actin binding motif in a Legionella pneumophila lysine fatty acyltransferase

    Wenjie W Zeng, Garrison Komaniecki ... Yuxin Mao
    A novel F-actin-binding motif consisting of an α-helix hairpin from a Legionella pneumophila lysine fatty acyltransferase has the potential to be developed as an F-actin probe.
    1. Epidemiology and Global Health

    Global risk mapping of highly pathogenic avian influenza H5N1 and H5Nx in the light of epidemic episodes occurring from 2020 onwards

    Marie-Cécile Dupas, Maria F Vincenti-Gonzalez ... Simon Dellicour
    Post-2020, highly pathogenic avian influenza H5 circulation is characterised by spatially expanded ecological suitability, changes in key environmental predictors, and a wider range of avian species affected.