Browse our Research Articles

Page 2 of 1,448
    1. Structural Biology and Molecular Biophysics

    Nucleosome wrapping energy in CpG islands and the role of epigenetic base modifications

    Rasa Giniūnaitė, Rahul Sharma ... Daiva Petkevičiūtė-Gerlach
    CpG density and epigenetic modification state modulate DNA mechanics, altering its intrinsic compatibility with nucleosome formation.
    1. Neuroscience

    Vascular endothelial-specific loss of TGF-beta signaling as a model for choroidal neovascularization and central nervous system vascular inflammation

    Yanshu Wang, Amir Rattner ... Jeremy Nathans
    In mice, loss of TGF-beta signaling specifically in vascular endothelial cells leads to retinal hypovascularization, choroidal neovascularization, a pro-inflammatory state within brain and retinal endothelial cells, and an influx of diverse inflammatory cells into the retina.
    1. Computational and Systems Biology
    2. Neuroscience

    Predictive modeling of hematoma expansion from non-contrast computed tomography in spontaneous intracerebral hemorrhage patients

    Natasha Ironside, Kareem El Naamani ... VISTA-ICH
    In spontaneous intracerebral hemorrhage patients, features of hematoma expansion can be visualized and predicted from non-contrast computed tomography using transport-based morphometry.
    1. Microbiology and Infectious Disease

    Functional genomics reveals strain-specific genetic requirements conferring hypoxic growth in Mycobacterium intracellulare

    Yoshitaka Tateishi, Yuriko Ozeki ... Sohkichi Matsumoto
    Transposon sequencing analyses reveal that among genomically diverse clinical Mycobacterium intracellulare strains and the type strain, 131 genes were comprehensively identified as universal essential genes suggesting promising drug targets.
    1. Developmental Biology
    2. Genetics and Genomics

    Computer prediction and genetic analysis identifies retinoic acid modulation as a driver of conserved longevity pathways in genetically diverse Caenorhabditis nematodes

    Stephen A Banse, Christine A Sedore ... Patrick C Phillips
    Computer screening identifies that the widely prescribed vitamin A derivative all-trans retinoic acid increases both longevity and late-life health in a powerful genetic model system.
    1. Medicine
    2. Neuroscience

    GPR30 in spinal cholecystokinin-positive neurons modulates neuropathic pain

    Qing Chen, Hui Wu ... Xinzhong Chen
    A combination of viral strategies, electrophysiological methods, and behavioral tests reveals how GPR30 in spinal CCK+ neurons modulates neuropathic pain.
    1. Medicine

    Are peer reviewers influenced by their work being cited?

    Adrian Barnett
    Some requests by reviewers to cite their own publications are coercive and can unnecessarily delay indexation and publication.
    1. Neuroscience

    Regional heterogeneities of oligodendrocytes underlie biased Ranvier node spacing along single axons in sound localization circuit

    Ryo Egawa, Kota Hiraga ... Hiroshi Kuba
    Oligodendrocytes with different morphological features work together to support precise binaural integration for sound localization in the chick brainstem auditory circuit.
    1. Evolutionary Biology

    Cryptovaranoides is not a squamate

    Michael W Caldwell, Chase D Brownstein ... Tiago R Simões
    Claims for a Triassic-aged crown lizard merit detailed reanalysis, the results of which find that Cryptovaranoides is not only not a lizard, but is a more distantly related diapsid reptile.