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Large-scale all-atom simulations of a full-length, glycosylated HIV-1 Env trimer in an asymmetric membrane reveal a rigid ectodomain and highly diverse conformational landscapes in the membrane-proximal region and transmembrane domain.

Chi3l1 binding to glucose protects Kupffer cells and limits MASLD progression.

Malaria importation in Matutuine district from southern Mozambique is strongly contributing to sustaining transmission, with Inhambane province being the main source of importation.

The viral type 2 internal ribosome entry site uses a unique mechanism to hijack the host ribosomal machinery by interacting with initiator tRNA and 40S head.

Whole-cell recordings paired with a network model show that post-inhibitory rebound excitation in premotor neurons couples intrinsic excitability to the temporal structure of learned birdsong.

Active biofilm carpets generate Mexican-wave-like synchronized dynamics and topological defects through nonreciprocal pili interactions.

Mycobacterium tuberculosis rewires central carbon metabolism to circumvent iron-dependent metabolic routes during iron starvation.

Proline hydroxylation of RepoMan (CDCA2) at P604 by PHD1 is shown to be important for mitotic progression and regulating interaction with PP2A regulatory subunit B56 gamma.

A robust workflow for the identification of proline hydroxylation sites in proteins was established, using hydrophilic interaction chromatography enrichment and LC-MS/MS together with refining and filtering parameters during data analysis.

Speaker identity is a distinguishing feature at birth and highlights the episodic nature of humans’ first-stored verbal memories.