Browse our Research Articles

Page 2 of 1,477
    1. Cell Biology

    Orderly mitosis shapes interphase genome architecture

    Krishnendu Guin, Adib Keikhosravi ... Tom Misteli
    High-throughput CRISPR-KO imaging screens reveal that disruption of mitotic processes impairs spatial genome organization in daughter cells.
    1. Microbiology and Infectious Disease

    Antibiotic potentiation and inhibition of cross-resistance in pathogens associated with cystic fibrosis

    Nikol Kadeřábková, R Christopher D Furniss ... Despoina AI Mavridou
    Targeting disulfide bond formation disables multiple antibiotic resistance mechanisms and prevents cross-protection between pathogens associated with cystic fibrosis lung infections, restoring antibiotic efficacy in polymicrobial settings.
    1. Neuroscience

    Dimorphic neural network architecture prioritizes sexual-related behaviors in male Caenorhabditis elegans

    Xuebin Wang, Hanzhang Liu ... He Liu
    Graph theory and computational modeling reveal that neural network architecture biases the male Caenorhabditis elegans brain toward prioritized sexual behaviors.
    1. Neuroscience

    Alpha-band phase modulates perceptual sensitivity by changing internal noise and sensory tuning

    April Pilipenko, Alexandra McGowan, Jason Samaha
    Alpha-band, 8–13 Hz, neural oscillations phasically modulate the sensitivity of visual detection by changing internal sensory noise.
    1. Neuroscience

    How individual vigor shapes human–human physical interaction

    Dorian Verdel, Bastien Berret, Etienne Burdet
    Interactions between pairs of humans lead to the emergence of a dyadic vigor with similar characteristics as individual vigor, where both partners adapt, with the slower having a critical role.
    1. Structural Biology and Molecular Biophysics

    Structural mechanisms of pump assembly and drug transport in the AcrAB–TolC efflux system

    Xiaofei Ge, Zhiwei Gu, Jiawei Wang
    High‑resolution cryo‑EM structures uncover YbjP as a novel lipoprotein that positions TolC and supports conformational changes in E. coli drug efflux pumps mediating antibiotic resistance.
    1. Neuroscience

    Modality-agnostic decoding of vision and language from fMRI

    Mitja Nikolaus, Milad Mozafari ... Rufin VanRullen
    Modality-agnostic decoders leverage modality-invariant representations in human subjects' brain activity to predict stimuli irrespective of their modality (image, text, mental imagery).
    1. Developmental Biology

    Cdhr1a and pcdh15b may link photoreceptor outer segments with calyceal processes revealing a potential mechanism for cone-rod dystrophy

    Meet K Patel, Warlen Pereira Piedade, Jakub K Famulski
    Zebrafish cone photoreceptor outer segment integrity may be regulated by the interactions between the outer segments and calyceal processes mediated by retinal cadherins cdhr1a and pcdh15b.
    1. Physics of Living Systems

    Fragmentation and aggregation of cyanobacterial colonies

    Yuri Z Sinzato, Robert Uittenbogaard ... Maziyar Jalaal
    Flow experiments show how the formation of cyanobacterial colonies is driven by cell division, aggregation, and fragmentation under different hydrodynamic conditions.
    1. Cancer Biology

    PTEN restrains SHH medulloblastoma growth through cell autonomous and nonautonomous mechanisms

    Zhimin Lao, Salsabiel El Nagar ... Alexandra L Joyner
    Homozygous but not heterozygous loss of Pten in sporadic mouse models of SHH-medulloblastoma greatly accelerates tumor formation, not metastasis, through increased survival of differentiated cells and possibly decreased infiltrating macrophages.