Neuroscience

Latest articles

1. 1. Cell Biology
   2. Neuroscience

   Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier

   Mariana I Tsap, Andriy S Yatsenko ... Halyna R Shcherbata

   Drosophila model reveals that NTE/SWS-associated neurodegeneration is a lysosomal storage disorder accompanied by a leaky brain permeability barrier, abnormal fatty acid metabolism, and inflammation.
2. 1. Neuroscience

   Inferring control objectives in a virtual balancing task in humans and monkeys

   Mohsen Sadeghi, Reza Sharif Razavian ... Dagmar Sternad

   A virtual balancing task with parallel experiments on human and non-human primates revealed a spectrum of behaviors (classified by a computational model into position, velocity, or mixed control strategy) that can serve as basis for analyzing neural population dynamics.
3. 1. Neuroscience

   Retinal metabolism displays evidence for uncoupling of glycolysis and oxidative phosphorylation via Cori-, Cahill-, and mini-Krebs-cycle

   Yiyi Chen, Laimdota Zizmare ... Christoph Trautwein

   Targeted manipulations on organotypic cultures show that the retina switches between at least four different metabolic pathways, each with different yields and kinetics, to dynamically adapt to momentaneous energy needs.
4. 1. Neuroscience

   A novel method for estimating properties of attentional oscillators reveals an age-related decline in flexibility

   Ece Kaya, Sonja A. Kotz, Molly J. Henry
5. 1. Neuroscience

   Why the brown ghost chirps at night

   Livio Oboti, Federico Pedraja ... Rüdiger Krahe
6. 1. Neuroscience

   Dynamic reinforcement learning reveals time-dependent shifts in strategy during reward learning

   Sarah Jo C Venditto, Kevin J Miller ... Nathaniel D Daw
7. 1. Medicine
   2. Neuroscience

   Txnip deletions and missense alleles prolong the survival of cones in a retinitis pigmentosa mouse model

   Yunlu Xue, Yimin Zhou, Constance L Cepko

   Multiple alleles of Txnip, which can interact with several different proteins, including Hsp90AB1, were tested for their ability to prolong the survival of cone photoreceptors in diseases leading to blindness.
8. 1. Neuroscience

   Parallel processing of quickly and slowly mobilized reserve vesicles in hippocampal synapses

   Juan Jose Rodriguez Gotor, Kashif Mahfooz ... John F Wesseling

   Reevaluation of reserve synaptic vesicle pools supports a new model of presynaptic function.
9. 1. Evolutionary Biology
   2. Neuroscience

   Large-scale deorphanization of Nematostella vectensis neuropeptide G protein-coupled receptors supports the independent expansion of bilaterian and cnidarian peptidergic systems

   Daniel Thiel, Luis Alfonso Yañez Guerra ... Gáspár Jékely

   The identification of 31 neuropeptide GPCRs in the sea anemone Nematostella vectensis provides a rich resource to study peptidergic signaling in cnidarians and suggests that cnidarian and bilaterian peptidergic systems diversified independent from each other from a few ancestral systems.
10. 1. Neuroscience

    Knockdown of PHOX2B in the retrotrapezoid nucleus reduces the central CO₂ chemoreflex in rats

    Silvia Cardani, Tara A Janes ... Silvia Pagliardini

    Knockdown of PHOX2B in the chemosensitive area of the retrotrapezoid nucleus of adult rats reduces CO₂ responses and the expression of the proton sensors TASK2 and GPR4.