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Page 2 of 229
Amyloid and tau accumulate across distinct spatial networks and are differentially associated with brain connectivity
Joana B Pereira et al.
Genetics and Genomics
Probe-Seq enables transcriptional profiling of specific cell types from heterogeneous tissue by RNA-based isolation
Ryoji Amamoto et al.
Probe-Seq is a cell type specific bulk RNA sequencing method that can be applied to a wide-ranging tissue types from both vertebrates and invertebrates without genetic labeling.
Calpain fosters the hyperexcitability of motoneurons after spinal cord injury and leads to spasticity
Vanessa Plantier et al.
Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis
Youngsik Woo et al.
Structural Biology and Molecular Biophysics
Two new polymorphic structures of human full-length alpha-synuclein fibrils solved by cryo-electron microscopy
Ricardo Guerrero-Ferreira et al.
One-shot learning and behavioral eligibility traces in sequential decision making
Marco P Lehmann et al.
Human learning relies on short-term memories (eligibility traces) which provide a mechanism to reinforce sequences of actions from a single reward (one-shot).
DeepPoseKit, a software toolkit for fast and robust animal pose estimation using deep learning
Jacob M Graving et al.
A new deep-learning software toolkit with general-purpose methods for quickly and reliably measuring the full body posture of animals directly from images or videos without physical markers.
model of neuronal ceroid lipofuscinosis
reveals a hypermorphic gain of function mechanism
Elliot Imler et al.
Genetic analysis of a
model suggests that the disease-causing alleles act as dominant gain of function mutations that cause CSPα oligomerization and impair secretory and prelysosomal trafficking.
Neurodegeneration: Fly model sheds light on brain disease
Martin H Berryer et al.
Experiments on flies suggest that a gain-of-function mechanism in a protein called CSPɑ contributes to the progressive brain disease CLN4.
Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons
Max Koppers et al.
Multiple axonal guidance receptors control the local and selective translation of mRNAs by binding to ribosomes, specific mRNAs and RNA-binding proteins.
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