Browse our latest Neuroscience articles

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    1. Neuroscience

    Control of adaptive action selection by secondary motor cortex during flexible visual categorization

    Tian-Yi Wang et al.
    The secondary motor cortex causally contributes to flexible action selection during stimulus categorization with the representations of upcoming choice and sensory history regulated by the demand to remap stimulus–action association.
    1. Neuroscience

    Gradients in the biophysical properties of neonatal auditory neurons align with synaptic contact position and the intensity coding map of inner hair cells

    Alexander L Markowitz, Radha Kalluri
    The biophysical diversity that is intrinsic to spiral ganglion neurons emerges as spatial gradients during early post-natal development and endures through subsequent maturation to likely contribute to sound intensity coding.
    1. Neuroscience

    Aberrant sorting of hippocampal complex pyramidal cells in type I lissencephaly alters topological innervation

    James A D'Amour et al.
    The loss of lamination in mammalian brain structures under cellular heterotopia carries with it non-uniform ramifications for the various components of the canonical CA1 microcircuitry.
    1. Neuroscience

    Long-term implicit memory for sequential auditory patterns in humans

    Roberta Bianco et al.
    Human listeners rapidly form robust, long lasting (up to 7 weeks) memories of rarely encountered, featureless sound sequences presented among many similar stimuli.
    1. Neuroscience

    Flexible motor sequence generation during stereotyped escape responses

    Yuan Wang et al.
    Time-ordered and flexible motor sequences in C.elegans are generated by combining an excitatory feedforward coupling and mutual inhibitions between neurons in different functional modules.
    1. Neuroscience

    Microglia TREM2R47H Alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels

    Siqiang Ren et al.
    Analysis of rats carrying the microglia gene and Alzheimer risk factor Trem2R47H variant shows increased glutamatergic transmission via supraphysiological TNF-α brain concentrations, linking a microglia pathogenic variant to neuronal dysfunction.