Browse our latest Neuroscience articles

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    1. Neuroscience

    Multiplexed CRISPRi reveals a transcriptional switch between KLF activators and repressors in the maturing neocortex

    Ryan W Kirk, Liwei Sun ... Sacha B Nelson
    In mammalian neocortex, opposing Krüppel-like factor (KLF) transcription factors first activate and then repress a genetic program related to axon outgrowth, potentially contributing to loss of cortical axon outgrowth in the adult.
    1. Neuroscience

    A reinforcement learning framework for goal-directed stimulation of engineered neuronal networks

    Benedikt Maurer, Vaiva Vasiliauskaitė ... Stephan J Ihle
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Theta phase and theta-gamma coupling organise the spoken language network

    Haya Akkad, Daniel Bush ... Jenny Crinion
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Developmental Biology
    2. Neuroscience

    Glia regulate local retinoic acid levels to specify neuronal specialisation for high-acuity vision

    Manuela Lahne, Roxana Lungu ... Ryan B MacDonald
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Identifying Novel Estrogenic Mitochondrial Targets in Hypothalamic Proopiomelanocortin Neurons by Chemoproteomics

    Jian Qiu, Martha A Bosch ... Martin J Kelly
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Neuroscience

    Real-Time Embodied Experience Shapes High-Level Reasoning Under Altered Gravity

    Hélène Grandchamp des Raux, Tommaso Ghilardi ... Ori Ossmy
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    • Incomplete
    1. Neuroscience

    Single neurons detect spatiotemporal activity transitions through STP and EI imbalance

    Aditya Asopa, Upinder Singh Bhalla
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    In vivo virus-free lineage tracing and live imaging reveal that NeuroD1 does not reprogram microglia into neurons

    Xiaoyu Li, Yuxin Li ... Yanxia Rao
    Genetic lineage tracing and live-cell imaging demonstrate that NeuroD1 does not convert microglia into neurons but instead promotes microglial apoptosis, challenging claims of in situ glia-to-neuron conversion.
    Version of Record
    Short Report
    • Important
    • Compelling
    1. Neuroscience

    Individual dopaminergic neurons induce unique, yet overlapping combinations of behavioural modulations, including safety learning, memory retrieval, and acute locomotion

    Naoko Toshima, Arman Behrad ... Michael Schleyer
    Carrying 'teaching' signals and modulating movement, two highly conserved functions of the dopaminergic system across all animals, are brought about by the same individual dopaminergic neurons in an insect larva.
    1. Neuroscience

    Domain-general computational integration in the Sense of Agency

    Amir Harduf, Ophir Netzer ... Roy Salomon
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
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