Figure 5—figure supplement 1. | Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice

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Transient rapamycin treatment can increase lifespan and healthspan in middle-aged mice

Figure 5—figure supplement 1.

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University of Washington, United States; Fred Hutchinson Cancer Research Center, United States; University of Missouri, United States
Figure 5—figure supplement 1.
Download figureOpen in new tabFigure 5—figure supplement 1. Rapamycin decreases fecal pellet size persistently after cessation of treatment.

(A) Weight of freshly excreted fecal pellets collected from rapamycin-injected and vehicle-injected male animals at 3 months of the treatment. N = 13 Vehicle, N = 19 Rapamycin. (B) Weight of fecal pellets collected from rapamycin-injected and vehicle-injected animals 1 month after cessation of the treatment. N = 71 vehicle female, N = 90 rapamycin female, N = 47 vehicle male, N = 36 rapamycin male. (C) Weight of fecal pellets collected from rapamycin-injected and vehicle-injected animals 4 months after cessation of the treatment. N = 22 vehicle female, N = 21 rapamycin female, N = 23 vehicle male, N = 22 rapamycin male. Data are indicated as mean ± s.e.m. *p<0.05. **p<0.01. ***p<0.001.

DOI: http://dx.doi.org/10.7554/eLife.16351.023