Figure 6. | Eco-HAB as a fully automated and ecologically relevant assessment of social impairments in mouse models of autism

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Eco-HAB as a fully automated and ecologically relevant assessment of social impairments in mouse models of autism

Figure 6.

Affiliation details

Nencki Institute of Experimental Biology of Polish Academy of Sciences, Poland; Polish Academy of Sciences, Poland; Warsaw University of Technology, Poland; University of Zurich, Switzerland; Kwazulu-Natal University Durban, Republic of South Africa
Figure 6.
Download figureOpen in new tabFigure 6. Assessment of approach to social odor in Fmr1 knockouts and respective littermate controls performed in two different laboratories.

(a, Fmr1 knockout n = 22, wild-type control n = 18) vs. (b, Fmr1 knockout n = 11, wild-type control n = 9). Regardless of experimental environment, evaluation carried out in Eco-HAB revealed comparable impairment in Fmr1 knockouts. Presented data are logarithmic values.

DOI: http://dx.doi.org/10.7554/eLife.19532.025

Figure 6—source data 1.We include source data for Figures 6, 7 and 8 concerning reproducibility results of both Eco-HAB measures.

The names of the Excel sheets refer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see 'Materials and methods').

DOI: http://dx.doi.org/10.7554/eLife.19532.026

Download source data [figure-6—source-data-1.media-10.xlsx]
Figure 6—source data 2.We include source data for Figures 6, 7 and 8 concerning reproducibility results of both Eco-HAB measures.

The names of the Excel sheetsrefer to corresponding figures and contain data used for analysis of the behavioral measures obtained by the implementation of Eco-HAB.py software (see Materials and methods).

DOI: http://dx.doi.org/10.7554/eLife.19532.027

Download source data [figure-6—source-data-2.media-11.xlsx]