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    1. Cell Biology
    2. Genetics and Genomics

    Male sex, BMI, smoking and depression all increase biological age

    A combined score of biological aging shows stronger links with physical and mental health than individual indicators.
    1. Epidemiology and Global Health

    Decision-support tool could reduce unnecessary antibiotic prescriptions for child diarrhoea

    Scientists present an advanced computer modelling tool that integrates real-time data and could help paediatricians determine if a child with diarrhoea needs antibiotics.
    1. Immunology and Inflammation

    Could playing host to hookworms help prevent ageing?

    Evidence is mounting to suggest that some helminth worms are ‘old friend’ commensals that can help us fight inflammation and prevent age-related disease.
    1. Cell Biology

    Potential drug target found for treating rare genetic disorder in children

    New study describes a potential drug target for Hutchinson-Gilford progeria syndrome that may aid in the development of more effective treatments.
    1. Biochemistry and Chemical Biology
    2. Medicine

    Iron release may contribute to cell death in heart failure

    A new study shows that the release of stored iron in heart cells may contribute to heart failure, suggesting potential new approaches to treatment.
  1. Media Coverage: January roundup of eLife papers in the news

    High-profile news coverage that eLife papers generated in January 2021, including Nature, The Scientist and Forbes.
    1. Microbiology and Infectious Disease

    Vaccine shows potential against deadly leptospirosis bacteria

    A potential vaccine protects hamsters and mice against death caused by multiple Leptospira species, and prevents kidney colonisation in mice.
    1. Plant Biology
    2. Structural Biology and Molecular Biophysics

    Scientists reveal structure of plants’ energy generators

    The first 3D structure of the components of the mitochondrial electron transport chain in plants reveals unique features that could help in herbicide and pesticide development.
    1. Evolutionary Biology

    Spike proteins of SARS-CoV-2 relatives can evolve against immune responses

    Viral relatives of SARS-CoV-2 can evolve to evade the human immune system, posing questions about the long-term effectiveness of COVID-19 vaccines.
    1. Genetics and Genomics

    How dietary choice influences lifespan in fruit flies

    Giving flies a choice of foods changes the chemical messaging in their brain that is responsible for coordinating metabolism, shortening their lifespan as a result.