Blocking peripheral opioid receptors with naloxone methiodide sufficiently prevents and reverses fentanyl-induced cardiorespiratory depression without causing the aversive effects of naloxone in rodents.
Combining intermittent fasting with localised Wnt3a treatments can rejuvenate bone repair in older mice, offering hope for reversing age-related tissue decline.
Toxoplasma gondii parasites can use secreted factors to compensate for genetic defects in neighbouring parasites, highlighting a limitation of pooled CRISPR screens.
A new gene-editing tool enables precise study of the variable proteins that allow malaria parasites to stick to red blood cells and evade the immune system.
Researchers have investigated how people adjust their risk-taking behaviours while being observed, providing new insights into the nuanced ways social context influences decision making.
A large UK study finds that the effects of menopausal hormone therapy on female brain health might vary depending on the duration of use and history of gynaecological surgery.
An analysis of leaf litter breakdown in climatically diverse habitats shows that decomposition by larger invertebrates dominates in hot, dry regions and warmer seasons.
