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  1. New drug target discovered for potential blood pressure treatment

    The PKD2 channel is involved in controlling blood pressure and activated differently in distinct blood vessels in the body.
  2. eLife supports SwipesForScience to gamify crowdsourced research and machine learning

    By helping scientists gamify the crowdsourcing of data analysis, SwipesForScience will engage the community to speed up research.
  3. Antibiotic could protect against neurodegenerative diseases during aging

    The antibiotic minocycline can increase the lifespan of aged roundworms and prevent the build-up of proteins, revealing a protective mechanism that could be exploited therapeutically to help prevent neurodegenerative diseases.
  4. Single-cell asymmetries control how groups of cells form 3D shapes together

    A new mathematical tool shows that altering one of two asymmetries in the properties of single cells controls how they organise into folded, biological shapes, and explains how such shapes are precisely reproduced and maintained.
  5. Study reveals how a small molecule promotes removal of excess cholesterol

    Researchers have determined the structure of an enzyme critical for the removal of excess cholesterol from the body, and bound to a chemical that boosts its activity, paving the way for potential new therapeutics to treat heart and kidney failure.
  6. Scientists identify potential target for treating rare cancer

    Degradation of the BRD9 protein presents a potential new opportunity for treating synovial sarcoma tumours.
  7. eLife, Coko, Hindawi Limited and Digirati commit to Libero for open-source publishing

    The development of a brand-new version of Libero will be governed under a model that puts the community at the heart of the project.
  8. Tropical fish adapt to cold temperatures in coordination with their microbiome

    Host genetics and innate temperature tolerance control the microbiome’s response to temperature changes in tropical fish, highlighting that the host and microbiome work together to adapt to stress.
  9. Scientists identify potential new treatment strategy for kidney cancer

    New study suggests activation of the protein ISGF3 could be a novel therapeutic strategy for patients with clear cell renal cancer.
  10. Warming oceans lead to more fur seal deaths from hookworm infection

    A new study suggests that, in warmer ocean temperatures, fur seal pups receive less maternal care and lack an effective immune response against hookworm infections as a result.