2,571 results found
    1. Cell Biology

    Two-signal requirement for growth-promoting function of Yap in hepatocytes

    Tian Su, Tanya Bondar ... Ruslan Medzhitov
    The Yap pathway requires two signals to promote organ growth: a cell intrinsic Hippo signal and a signal induced by injury or inflammation.
    1. Developmental Biology

    Neural tube-associated boundary caps are a major source of mural cells in the skin

    Gaspard Gerschenfeld, Fanny Coulpier ... Piotr Topilko
    Neural tube-associated boundary caps are heterogeneous with a non-neural crest-derived subpopulation that may originate from the developing meninges, which gives rise to derivatives that migrate along nerves to detach and differentiate into skin mural cells.
    1. Biochemistry and Chemical Biology
    2. Chromosomes and Gene Expression

    Elba, a novel developmentally regulated chromatin boundary factor is a hetero-tripartite DNA binding complex

    Tsutomu Aoki, Ali Sarkeshik ... Paul Schedl
    A chromatin boundary factor that is only active during early embryo development has been discovered in Drosophila.
    1. Chromosomes and Gene Expression

    Chromosome structure in Drosophila is determined by boundary pairing not loop extrusion

    Xinyang Bing, Wenfan Ke ... James B Jaynes
    Boundary:boundary pairing interactions drive TAD formation in Drosophila.
    1. Neuroscience

    Entorhinal-retrosplenial circuits for allocentric-egocentric transformation of boundary coding

    Joeri BG van Wijngaarden, Susanne S Babl, Hiroshi T Ito
    An extended border coding circuit across the entorhinal and retrosplenial cortex incorporates self-referenced and viewpoint-invariant boundary information to guide navigation behavior.
    1. Neuroscience

    Processing of motion boundary orientation in macaque V2

    Heng Ma, Pengcheng Li ... Haidong D Lu
    Area V2 in macaque monkeys contributes to the perception of the outlines of moving objects and achieves this through a local computation.
    1. Developmental Biology

    Actomyosin regulation by Eph receptor signaling couples boundary cell formation to border sharpness

    Jordi Cayuso, Qiling Xu ... David G Wilkinson
    Boundary cell identity and sharpening of borders are coupled in hindbrain development since both are regulated by mechanical tension.
    1. Chromosomes and Gene Expression

    Stem-loop and circle-loop TADs generated by directional pairing of boundary elements have distinct physical and regulatory properties

    Wenfan Ke, Miki Fujioka ... James B Jaynes
    Boundary:boundary pairing generates either stem-loop or circle-loop TADs, and these loop topologies differ in how they impact chromosome structure and genetic activities.
    1. Chromosomes and Gene Expression
    2. Developmental Biology

    lncRNA read-through regulates the BX-C insulator Fub-1

    Airat Ibragimov, Xin Yang Bing ... Paul Schedl
    A novel mechanism of gene regulation is discovered wherein a specific long non-coding RNA abolishes the blocking activity of chromatin insulator in the Drosophila HOX gene cluster.
    1. Cell Biology
    2. Developmental Biology

    Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates

    Martin L Basch, Rogers M Brown II ... Andrew K Groves
    The cochlea deploys two Fringe proteins at exactly the same time and position to regulate a novel mode of Notch signaling that sets the boundary of the organ of Corti, the ear's hearing organ.

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