Proteomics and metabolic modeling revealed that the 'knallgas' bacterium Cupriavidus necator utilizes only a fraction of its proteome and keeps large enzyme reserves as an adaption to variable environments.
Donato Giovannelli, Stefan M Sievert ... Costantino Vetriani
The genome of Thermovibrio ammonificans encodes ancestral pathways (e.g., hydrogen oxidation) and more recently acquired ones (e.g., nitrate reduction) and a hybrid pathway for CO2 fixation.
Achieving autotrophy in E. coli by introducing a small number of genetic changes crosses a milestone in engineering major metabolic transitions and paves a way for sustainable bio-production from CO2.
An unexpected new biological function was discovered for the universally conserved cofactor lipoate, as lipoate-binding proteins proved essential for a novel wide-spread prokaryotic sulfur oxidation pathway.
Carolina A Martinez-Gutierrez, Josef C Uyeda, Frank O Aylward
Phylogenomics reveals the timeline over which marine bacteria and archaea colonized the oceans and shows the geological context of their diversification.