The human cytomegalovirus US12 gene family work co-operatively to degrade large numbers of immune ligands and prevent recognition by natural killer cells.

Natural killer cells that were commonly thought to circulate around the body can actually reside in distinct tissues, such as in the liver, skin or uterus, and do not re-circulate.

CRISPR/Cas9 screens reveal a role for the ubiquitin ligase substrate adaptor DCAF15 in the immune surveillance of cancer cells by natural killer cells.

Extracellular vesicles derived from natural killer cells contain a specific repertoire of microRNAs that promote Th1 responses.

Genetically engineered, CD73-redirected human NK cells show potent antitumor activity in vivo by impairing adenosinergic activity of CD73 in cancer.

Deficiency of the transcriptional repressor, Bach2, results in more mature mouse natural killer cells.

The development of Natural Killer T Cells is controlled by Histone Deacetylase 7, a function that combined with its known role in thymic negative selection provides a potential mechanism explaining its association with tissue-specific autoimmunity in humans.

Forward genetic screening has provided insight into the molecular mechanisms and stress pathways that promote tumor cell recognition by natural killer cells.

Chronic engagement of Natural killer cell inhibitory receptors by MHC-I molecules maintains a high activity of the mTOR pathway allowing subsequent amplification of signaling through activating receptors upon acute stimulation.

Diagnosing the presence and clinical significance of prostate cancer can be achieved using AI-based analysis of peripheral blood natural killer (NK) cell subset profiles.