The ability to quickly re-acquire a previously lost motor skill is associated with lasting synaptic changes in the brain circuit that controls that motor skill.
Stefan M Lemke, Dhakshin S Ramanathan ... Karunesh Ganguly
Sleep spindles, distinctive brain activity patterns occurring in non-REM sleep, modify cross-area connectivity in the motor network relevant for behavioral flexibility, impacting subsequent behavior.
Fernando J Santos, Rodrigo F Oliveira ... Rui M Costa
Recordings from the mouse brain as animals learn a lever pressing task reveal how the motor system optimizes skill learning by reducing variability in those aspects of task performance that are essential for achieving a goal.
Homology of vertebrate skull structures should be based on evolutionary continuity and an appreciation of germ layer origins and inductive signaling in the embryonic head.
Michael A Kovacs, Maureen N Cowan ... Tajie H Harris
In the setting of CNS infection, meningeal lymphatic drainage promotes dendritic cell and T cell responses in the deep cervical lymph nodes but is not necessary for maintaining control of parasite in the brain.
Haya Akkad, Joshua Dupont-Hadwen ... Charlotte J Stagg
Driving theta–gamma activity in the human cortex with non-invasive brain stimulation enhances motor skill acquisition in healthy adults, revealing a potential neuroplastic mechanism that might be harnessed for therapeutic intervention.
Advanced models of diffusion-weighted imaging data reveal that intra-axonal volume, especially in left temporoparietal and cerebellar white matter, relates to reading skills in a dataset of 983 children and adolescents.
Studies in mice and neurons reveal how modulation of the axonal transport of synaptic vesicles via huntingtin phosphorylation influences the number of vesicles accumulating at the synapse, subsequent glutamate release, and behavior in mice.