13,860 results found
    1. Neuroscience

    Accelerated redevelopment of vocal skills is preceded by lasting reorganization of the song motor circuitry

    Michiel Vellema, Mariana Diales Rocha ... Manfred Gahr
    The ability to quickly re-acquire a previously lost motor skill is associated with lasting synaptic changes in the brain circuit that controls that motor skill.
    1. Neuroscience

    Cholecystokinin facilitates motor skill learning by modulating neuroplasticity in the motor cortex

    Hao Li, Jingyu Feng ... Jufang He
    CCK released from the neural projections from the rhinal cortex to the motor cortex modulates neural plasticity and facilitates motor skill learning.
    1. Neuroscience

    Coupling between motor cortex and striatum increases during sleep over long-term skill learning

    Stefan M Lemke, Dhakshin S Ramanathan ... Karunesh Ganguly
    Sleep spindles, distinctive brain activity patterns occurring in non-REM sleep, modify cross-area connectivity in the motor network relevant for behavioral flexibility, impacting subsequent behavior.
    1. Neuroscience

    Fatigue induces long-lasting detrimental changes in motor-skill learning

    Meret Branscheidt, Panagiotis Kassavetis ... Pablo Celnik
    A series of experiments shows how muscle fatigue impairs motor-skill learning on subsequent practice days beyond its effects on task execution.
    1. Neuroscience

    Corticostriatal dynamics encode the refinement of specific behavioral variability during skill learning

    Fernando J Santos, Rodrigo F Oliveira ... Rui M Costa
    Recordings from the mouse brain as animals learn a lever pressing task reveal how the motor system optimizes skill learning by reducing variability in those aspects of task performance that are essential for achieving a goal.
    1. Developmental Biology
    2. Evolutionary Biology

    Resolving homology in the face of shifting germ layer origins: Lessons from a major skull vault boundary

    Camilla S Teng, Lionel Cavin ... J Gage Crump
    Homology of vertebrate skull structures should be based on evolutionary continuity and an appreciation of germ layer origins and inductive signaling in the embryonic head.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Meningeal lymphatic drainage promotes T cell responses against Toxoplasma gondii but is dispensable for parasite control in the brain

    Michael A Kovacs, Maureen N Cowan ... Tajie H Harris
    In the setting of CNS infection, meningeal lymphatic drainage promotes dendritic cell and T cell responses in the deep cervical lymph nodes but is not necessary for maintaining control of parasite in the brain.
    1. Neuroscience

    Increasing human motor skill acquisition by driving theta–gamma coupling

    Haya Akkad, Joshua Dupont-Hadwen ... Charlotte J Stagg
    Driving theta–gamma activity in the human cortex with non-invasive brain stimulation enhances motor skill acquisition in healthy adults, revealing a potential neuroplastic mechanism that might be harnessed for therapeutic intervention.
    1. Neuroscience

    Fiber-specific structural properties relate to reading skills in children and adolescents

    Steven Lee Meisler, John DE Gabrieli
    Advanced models of diffusion-weighted imaging data reveal that intra-axonal volume, especially in left temporoparietal and cerebellar white matter, relates to reading skills in a dataset of 983 children and adolescents.
    1. Neuroscience

    Huntingtin recruits KIF1A to transport synaptic vesicle precursors along the mouse axon to support synaptic transmission and motor skill learning

    Hélène Vitet, Julie Bruyère ... Frédéric Saudou
    Studies in mice and neurons reveal how modulation of the axonal transport of synaptic vesicles via huntingtin phosphorylation influences the number of vesicles accumulating at the synapse, subsequent glutamate release, and behavior in mice.

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