13 results found
    1. Developmental Biology

    Coordination of cell cycle and morphogenesis during organ formation

    Jeffrey Matthew, Vishakha Vishwakarma ... SeYeon Chung
    The SP1/KLF transcription factor Huckebein controls endoreplication in the Drosophila salivary gland, ensuring proper morphogenesis during organ formation.
    1. Developmental Biology

    Decoding temporal interpretation of the morphogen Bicoid in the early Drosophila embryo

    Anqi Huang, Christopher Amourda ... Timothy E Saunders
    Cell fates endowed by higher Bicoid concentration require input for longer duration, demonstrating a temporally non-linear morphogen-mediated pattern formation.
    1. Developmental Biology
    2. Genetics and Genomics

    Establishment of regions of genomic activity during the Drosophila maternal to zygotic transition

    Xiao-Yong Li, Melissa M Harrison ... Michael B Eisen
    Drosophila melanogaster embryos undergo a dramatic genomic transformation in the hour preceding gastrulation, as thousands of promoters and regulatory regions become biochemically distinct before they become active.
    1. Developmental Biology
    2. Evolutionary Biology

    Quantitative system drift compensates for altered maternal inputs to the gap gene network of the scuttle fly Megaselia abdita

    Karl R Wotton, Eva Jiménez-Guri ... Johannes Jaeger
    Quantitative system-level analysis of a pattern-forming gene regulatory network in a non-model organism shows that dynamic changes in gene expression evolve through quantitative system drift.
    1. Developmental Biology

    Functional evolution of a morphogenetic gradient

    Chun Wai Kwan, Jackie Gavin-Smyth ... Urs Schmidt-Ott
    BMP guides the evolution of extraembryonic tissue complexity in fly embryos through changes in the control of a positive feedback circuit.
    1. Cell Biology
    2. Developmental Biology

    Correct regionalization of a tissue primordium is essential for coordinated morphogenesis

    Yara E Sánchez-Corrales, Guy B Blanchard, Katja Röper
    During the morphogenesis of the tubes of the salivary glands in the fly embryo, a correct regionalization of the flat epithelial primordium by upstream transcription factors is key to drive coordinated changes in cell behavior.
    1. Cell Biology
    2. Developmental Biology

    Uncoupling apical constriction from tissue invagination

    SeYeon Chung, Sangjoon Kim, Deborah J Andrew
    Spatially coordinated apical constriction occurs during Drosophila salivary gland invagination, but the salivary gland can form fully internalized and elongated tubes even when this process is completely blocked.
    1. Developmental Biology
    2. Chromosomes and Gene Expression

    Establishment and maintenance of heritable chromatin structure during early Drosophila embryogenesis

    Shelby A Blythe, Eric F Wieschaus
    The patterns of chromatin architecture that underlie the initial embryonic cell fate decisions are established during a period of intense cell cycle activity, and these patterns are stably maintained even in highly condensed mitotic chromatin.
    1. Developmental Biology

    Antagonism between germ cell-less and Torso receptor regulates transcriptional quiescence underlying germline/soma distinction

    Megan M Colonnetta, Lauren R Lym ... Girish Deshpande
    A molecular duel between germline and somatic determinants ensures proper establishment of transcriptional quiescence in the primordial germ cells of early Drosophila embryos.
    1. Developmental Biology

    The Hox transcription factor Ubx stabilizes lineage commitment by suppressing cellular plasticity in Drosophila

    Katrin Domsch, Julie Carnesecchi ... Ingrid Lohmann
    The Hox transcription factor Ultrabithorax (Ubx) represses alternative gene programs during lineage development by lineage-specific Polycomb protein complex retention at Ubx-targeted chromatin sites.

Refine your results by:

Type
Research categories