2,682 results found
    1. Neuroscience

    When and why does motor preparation arise in recurrent neural network models of motor control?

    Marine Schimel, Ta-Chu Kao, Guillaume Hennequin
    A computational model shows that preparation arises as an optimal control strategy in input-driven recurrent neural networks performing a delayed-reaching task.
    1. Neuroscience

    Minimally dependent activity subspaces for working memory and motor preparation in the lateral prefrontal cortex

    Cheng Tang, Roger Herikstad ... Shih-Cheng Yen
    The evidence of subspace computation in the lateral prefrontal cortex provides insights into the neural mechanisms underlying cognitive flexibility and interference between different cognitive processes.
    1. Neuroscience

    Mechanisms that allow cortical preparatory activity without inappropriate movement

    Timothy R Darlington, Stephen G Lisberger
    The use of preparatory activity in the smooth eye movement region of the frontal eye fields as a visual-motor gain signal allows preparation to progress without inappropriate movement.
    1. Neuroscience

    Interplay between external inputs and recurrent dynamics during movement preparation and execution in a network model of motor cortex

    Ludovica Bachschmid-Romano, Nicholas G Hatsopoulos, Nicolas Brunel
    A recurrent neural network model with parameters constrained by data explains mechanisms for how tuning properties of motor cortical neurons change during movement preparation and execution in a monkey performing a reaching task, and accurately reproduces neural dynamics from recordings.
    1. Neuroscience

    I-Spin live, an open-source software based on blind-source separation for real-time decoding of motor unit activity in humans

    Julien Rossato, François Hug ... Simon Avrillon
    I-Spin enables researchers to decode motor unit firings from surface and intramuscular electromyographic signals in real time.
    1. Neuroscience

    Conservation of preparatory neural events in monkey motor cortex regardless of how movement is initiated

    Antonio H Lara, Gamaleldin F Elsayed ... Mark M Churchland
    Voluntary movements are preceded by a temporally flexible preparatory neural process that is present regardless of whether movement is initiated rapidly or thoughtfully.
    1. Neuroscience

    Multiphasic value biases in fast-paced decisions

    Elaine A Corbett, L Alexandra Martinez-Rodriguez ... Simon P Kelly
    Neurophysiological signatures of motor preparation reveal countervailing value biasing mechanisms that evolve across consecutive phases of anticipation, detection, and discrimination in sensorimotor decision making.
    1. Biochemistry and Chemical Biology

    Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes

    Cristian A Lasagna-Reeves, Maxime WC Rousseaux ... Huda Y Zoghbi
    Building on previous work (Lasagna-Reeves et al., 2015) it is shown that polyglutamine ATXN1 oligomers propagate locally in SCA1 mice, and that passive immunotherapy targeting soluble oligomers can lead to an improvement in motor coordination and a modest increase in life span.
    1. Neuroscience

    Organelle calcium-derived voltage oscillations in pacemaker neurons drive the motor program for food-seeking behavior in Aplysia

    Alexis Bédécarrats, Laura Puygrenier ... Romuald Nargeot
    An atypical neuronal pacemaker mechanism triggers feeding motor pattern in Aplysia..
    1. Neuroscience
    2. Physics of Living Systems

    Beta oscillations and waves in motor cortex can be accounted for by the interplay of spatially structured connectivity and fluctuating inputs

    Ling Kang, Jonas Ranft, Vincent Hakim
    The observed activity of the motor cortex in space and time is reproduced by a model with a specific structure of the inputs to the motor cortex.

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