Bayesian simulator-based inference is used to infer the parameters of complex multicompartment models of retinal neurons from two-photon imaging data.

Extracellular vesicles are proposed as novel, non-cell-autonomous mediators of neuronal atrophy in Parkinson's disease.

Apical and basal dendrites contribute differently to single-neuron orientation selectivity, highlighting the impact of feedforward and feedback signal interactions.

Biologically plausible levels of myelin dystrophy induce substantial working memory impairment in a computational model of brain aging across two spatial and temporal scales.

Parallel input streams to layer 1 identify a computationally distinct principal neuronal subtype ideally positioned to support spatial orientation computations in the granular retrosplenial cortex.

Electrical activity at the gonadotropin-releasing hormone (GnRH) neuron cell body and proximal dendrites is not required for the pulsatile secretion of GnRH that controls fertility.

Brian 2 is a software package for neural simulations that makes it both easy and computationally efficient to define original models for computational experiment.

Spontaneous theta oscillations and interneuron-specific phase preferences emerge spontaneously in a full-scale model of the isolated hippocampal CA1 subfield, corroborating and extending recent experimental findings.

Biophysically realistic computational model reveals how inhibitory interneurons initiate paroxysmal discharges and how changes in the ionic concentrations shape electrographic features of human seizures.

Electrophysiological recordings and a large-scale biophysical model show that a unique inhibitory neuron plays a central role in structuring olfactory codes in the insect brain.