Browse our latest Cancer Biology articles

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    1. Genetics and Genomics
    2. Cancer Biology

    DUX4 is a common driver of immune evasion and immunotherapy failure in metastatic cancers

    Jose Mario Bello Pineda, Robert K. Bradley
    1. Computational and Systems Biology
    2. Cancer Biology

    Optimal transport for automatic alignment of untargeted metabolomic data

    Marie Breeur, George Stepaniants ... Vivian Viallon
    1. Cancer Biology
    2. Cell Biology

    N-cadherin directs the collective Schwann cell migration required for nerve regeneration through Slit2/3 mediated contact inhibition of locomotion

    Julian J A Hoving, Elizabeth Harford-Wright ... Alison C Lloyd
    1. Cell Biology
    2. Cancer Biology

    mitoBKCa is functionally expressed in murine and human breast cancer cells and potentially contributes to metabolic reprogramming

    Helmut Bischof, Selina Maier ... Robert Lukowski
    1. Cancer Biology
    2. Structural Biology and Molecular Biophysics

    The molecular basis of Abelson kinase regulation by its αI-helix

    Johannes Paladini, Annalena Maier ... Stephan Grzesiek
    High-resolution NMR data and precise kinase activity assays on Abelson kinase bearing mutations in its αI-helix identify the αI-helix parts involved in disassembly of Abelson’s regulatory core and kinase activation.
    1. Genetics and Genomics
    2. Cancer Biology

    Single cell multi-omics analysis of chronic myeloid leukemia links cellular heterogeneity to therapy response

    Rebecca Warfvinge, Linda Geironson Ulfsson ... Göran Karlsson
    1. Cancer Biology

    DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation

    Nicholas J. Mullen, Surendra K. Shukla ... Pankaj K. Singh
    1. Biochemistry and Chemical Biology
    2. Cancer Biology

    DePARylation is critical for S phase progression and cell survival

    Litong Nie, Chao Wang ... Junjie Chen
    DePARylation is essential for cell survival and thus poly(ADP-ribose) glycohydrolase (PARG) expression correlates with cytotoxicity induced by PARG inhibition, which will benefit the development of PARG inhibitors for cancer treatment.
    1. Cell Biology
    2. Cancer Biology

    SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells

    Linda Zhang, Joanne I. Hsu ... Margaret A. Goodell
    1. Cancer Biology

    STAT3 is a genetic modifier of TGF-beta induced EMT in KRAS mutant pancreatic cancer

    Stephen D'Amico, Varvara Kirillov ... Nancy C Reich
    Results show that STAT3 and KRAS jointly regulate oncogenic dependency of mutant KRAS cancer cells.
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