Browse our latest Cancer Biology articles

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    1. Cancer Biology
    2. Cell Biology

    EPAC1 inhibition protects the heart from doxorubicin-induced toxicity

    Marianne Mazevet, Anissa Belhadef ... Eric Morel
    The inhibition of EPAC1, a cAMP-binding protein, appears as a potential therapeutic strategy to limit doxorubicin-induced cardiotoxicity without interfering with its antitumoral activity.
    1. Epidemiology and Global Health
    2. Medicine
    3. Cancer Biology

    Special Issue: The impact of the COVID-19 pandemic on cancer prevention, control, care and survivorship

    Edited by Eduardo Franco et al.
    Our latest Special Issue brings together research covering many different aspects of the impact of the COVID-19 pandemic on cancer outcomes across the globe.
    1. Cancer Biology
    2. Cell Biology

    Cancer Survivorship: Protecting the heart

    Joshua M Inglis, Arduino A Mangoni
    Blocking a protein known as EPAC1 may prevent the development of heart-related side effects caused by a chemotherapy drug.
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    1. Cancer Biology
    2. Computational and Systems Biology

    Spatial transformation of multi-omics data unlocks novel insights into cancer biology

    Mateo Sokač, Asbjørn Kjær ... Nicolai J Birkbak
    GENIUS provides a deep learning framework for multi-omics integration that transforms data into spatial images, using integrated gradients to reveal novel and critical cancer gene association.
    1. Cancer Biology

    Isoform-specific disruption of the TP73 gene reveals a critical role for TAp73γ in tumorigenesis via leptin

    Xiangmudong Kong, Wensheng Yan ... Xinbin Chen
    Mouse model reveals that TAp73γ functions as an oncogene to promote tumorigenesis and alter lipid metabolism by modulating leptin expression.