Browse our latest Cancer Biology articles

High-throughput characterization of all possible CDKN2A missense variants identifies functionally deleterious variants and establishes accuracy of variant effect predictors.

In a mouse model of the hotspot mutant TP53^Y220C, the mutant p53 exhibited oncogenic gain of function in males and teratogenic gain of function in females, both correlated with inflammation.

Tumor-suppressive protein FRMD8 inhibits breast cancer progression by regulating the level of ERα and has the possibility to be a potential target for overcoming tamoxifen treatment resistance.

STAMPBL1 activates the transcription of GRHL3 by interacting with FOXO1 in nucleus, thereby upregulating the HIF1α/VEGFA axis and promoting angiogenesis in TNBC tumors, independently of its DUB activity.

The crosstalk between cancerous lesions and the immune system in the lungs demonstrates the complex role of fibroblasts.

Identifying the regulators of a non-genetic mechanism (ERCYS) that is constitutively activated in cancer cells to provide pro-survival properties.

Single-cell imaging and mass spectrometry data reveal adenosine in the DNA of mammalian cells can be methylated by METTL3 to form N6-methyladenosine in response to DNA damage.