Browse our latest Cancer Biology articles

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    1. Cancer Biology
    2. Medicine

    Molecular feature-based classification of retroperitoneal liposarcoma: a prospective cohort study

    Mengmeng Xiao, Xiangji Li ... Li Min
    Identification of two molecularly distinct retroperitoneal liposarcoma subtypes, stratifiable via LEP and PTTG1 biomarkers, enables prognosis prediction and informs precision surgical strategies to improve clinical outcomes.
    1. Cell Biology
    2. Cancer Biology

    Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer

    Chong Zhang, Zuoyan Zhang ... Yangling Li
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Solid
    1. Cancer Biology

    ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1

    Jordina Rincon-Torroella, Marco Dal Molin ... Surojit Sur
    Monocarboxylate transporter 1 overexpressed pancreatic cancers can be therapeutically targeted with ME3BP-7, a promising new agent with unique mode of action.
    1. Cancer Biology

    TopBP1 biomolecular condensates: a new therapeutic target in advanced-stage colorectal cancer

    Laura Morano, Nadia Vezzio-Vié ... Jihane Basbous
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Computational and Systems Biology
    2. Cancer Biology

    Single-Cell Atlas of AML Reveals Age-Related Gene Regulatory Networks in t(8;21) AML

    Jessica Whittle, Stefan Meyer ... Mudassar Iqbal
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Computational and Systems Biology
    2. Cancer Biology

    Drug combination prediction for cancer treatment using disease-specific drug response profiles and single-cell transcriptional signatures

    Daniel Osorio, Parastoo Shahrouzi ... Marieke L Kuijjer
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cancer Biology
    2. Genetics and Genomics

    Transcriptional pattern enriched for synaptic signaling is associated with shorter survival of patients with high-grade serous ovarian cancer

    Arkajyoti Bhattacharya, Thijs S Stutvoet ... Rudolf SN Fehrmann
    Independent component analysis of ovarian cancer transcriptomes reveals distinct transcriptional patterns associated with overall survival.
    1. Cancer Biology

    Causal associations between plasma proteins and prostate cancer: a Proteome-Wide Mendelian Randomization

    Chen Lin, Rong Zhuona ... Pang Xiaocong
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Chromosomes and Gene Expression
    2. Cancer Biology

    Conserved and Unique Features of Terminal Telomeric Sequences in ALT-Positive Cancer Cells

    Benura Azeroglu, Wei Wu ... Eros Lazzerini Denchi
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Cell Biology
    2. Cancer Biology

    Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics

    David Papadopoli, Ranveer Palia ... Ivan Topisirovic
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
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