Browse our latest Cell Biology articles

Page 41 of 316
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Export of discarded splicing intermediates requires mRNA export factors and the nuclear basket

    Yi Zeng, Jonathan P. Staley
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Tead1 reciprocally regulates adult β-cell proliferation and function to maintain glucose homeostasis

    Jeongkyung Lee, Ruya Liu ... Vijay K. Yechoor
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Cell Biology

    Spatiotemporal dissection of the Golgi apparatus and the ER-Golgi intermediate compartment in budding yeast

    Takuro Tojima, Yasuyuki Suda ... Akihiko Nakano
    Spatiotemporal mapping of a variety of proteins in and around the Golgi apparatus in budding yeast was performed using super-resolution live imaging microscopy and identified the ER-Golgi intermediate compartment that matures into the Golgi.
    1. Cell Biology

    WRNIP1 prevents transcription-associated genomic instability

    Pasquale Valenzisi, Veronica Marabitti ... Annapaola Franchitto
    WRNIP1 has been identified as a pivotal factor in preventing the pathological persistence of R-loop-induced transcription-replication conflicts and the accumulation of DNA damage, thereby ensuring genome integrity.
    1. Cell Biology
    2. Developmental Biology

    Perirenal adipose tissue contains a subpopulation of cold-inducible adipocytes derived from brown-to-white conversion

    Houyu Zhang, Yan Li ... Meng Xie
    A brown-to-white adipogenic transdifferentiation process in the periureter region of mouse renal adipose tissue gives rise to a population of cold-inducible adipocytes with a transcriptome distinct from subcutaneous beige adipocytes.
    1. Cell Biology

    Sorting of secretory proteins at the trans-Golgi network by human TGN46

    Pablo Lujan, Carla Garcia-Cabau ... Felix Campelo
    TGN46 is a cargo receptor, with its luminal domain being necessary and sufficient to load soluble secretory proteins into transport carriers for export out of the trans-Golgi network.
    1. Cell Biology

    A novel imaging method (FIM-ID) reveals that myofibrillogenesis plays a major role in the mechanically induced growth of skeletal muscle

    Kent W Jorgenson, Jamie E Hibbert ... Troy A Hornberger
    A novel imaging method for measuring myofibril size/number reveals that the radial growth of muscle fibers that occurs in response to increased mechanical loading is largely mediated by myofibrillogenesis.
    1. Cell Biology

    Mapping variation in the morphological landscape of human cells with optical pooled CRISPRi screening

    Ramon Lorenzo D. Labitigan, Adrian L. Sanborn ... Julie A. Theriot
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology

    The ER tether VAPA is required for proper cell motility and anchors ER-PM contact sites to focal adhesions

    Hugo Siegfried, Georges Farkouh ... Mélina L Heuzé
    Depletion of VAPA in cancer cells induces defects in actin organization, adhesion dynamics and cell migration, together with a perturbation of phosphoinositide levels at the plasma membrane and a lack of anchoring of ER-PM contact sites to focal adhesions.
    1. Cell Biology
    2. Genetics and Genomics

    Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse

    Jana Muroňová, Zine Eddine Kherraf ... Christophe Arnoult
    CCDC146 is a structural component of the flagellum in sperm, located in the doublet microtubules of the axoneme, whose absence leads to multiple morphological anomalies of the flagellum.