Xinzhu Wei, Christopher R Robles ... Sriram Sankararaman
Genetic variants introgressed into modern humans from Neanderthals tend to be depleted in their contribution to heritable trait variation relative to modern human variants consistent with the action of purifying selection.
Several different mutations in the SARS-CoV-2 genome have occurred more times than expected by chance in either mink or deer infections, suggesting species-specific viral adaptations to these animals.
The mathematical model incorporating new parameters explains multimodal distributions in escape direction (i.e., multiple preferred escape trajectories), which are previously observed in various animal taxa.
Noah H Rose, Athanase Badolo ... Carolyn S McBride
The dengue and yellow fever mosquito first specialized on humans about 5000 years ago, but appears to use the same genes to thrive in urban environments today.
Zane Kliesmete, Lucas Esteban Wange ... Wolfgang Enard
Combining phylogenetic and functional approaches, it is shown that the protein sequence, the proliferative activity, and a regulatory element of TRNP1 co-evolve with brain size and folding.
The novel function of the evolutionarily conserved nutrient-sensing pathway TOR in the wing disc-specific autophagic degradation and development of wingless aphids.
A new framework for mutation spectrum analysis reveals multiple independent changes in the germline mutation patterns of human populations, which cannot be explained by shifts in average ages at reproduction.