Browse our latest Immunology and Inflammation articles

In silico modeling identify allosteric CXCR4 modulators that block receptor nanoclustering and chemoattractant sensing without affecting other CXCL12-mediated functions, and reduce tumorigenesis and metastasis in a zebrafish model.

ImmCellTyper enhances CyTOF data analysis by combining expert biological knowledge with advanced clustering tools to provide an accurate, comprehensive, and user-friendly solution for high-dimensional immune profiling.

A novel in vivo role for miRNAs Mir221/222 in arthritogenic synovial fibroblasts and progression of arthritis is presented.

Dermal preadipocytes produce T cell chemokines in response to IFNγ, driving the recruitment and activation of type 1 effector T cells in allergic contact dermatitis.

Bacteria release ATP as part of their attack in sepsis.

Fam49b is a critical regulator of selection process to ensure normal thymocyte development and peripheral T cells survival.

There is an ongoing need for researchers and all stakeholders to better understand issues surrounding antibody characterization to improve the quality and reproducibility of research that employs these reagents.