Browse our latest Immunology and Inflammation articles

Page 22 of 119
    1. Immunology and Inflammation

    Mir221/222 drive synovial hyperplasia and arthritis by targeting cell cycle inhibitors and chromatin remodeling components

    Fani Roumelioti, Christos Tzaferis ... George Kollias
    A novel in vivo role for miRNAs Mir221/222 in arthritogenic synovial fibroblasts and progression of arthritis is presented.
    1. Immunology and Inflammation

    Apoptotic caspases cleave DRP1 to promote mitochondrial fusion and anti-viral immune responses

    Yujie Fang, Zihan Guan ... Ke Peng
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Structural epitope profiling identifies antibodies associated with critical COVID-19 and long COVID

    Patrick KA Kearns, Charles Dixon ... Nick Gilbert
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation

    Defining cell type-specific immune responses in a mouse model of allergic contact dermatitis by single-cell transcriptomics

    Youxi Liu, Meimei Yin ... Ling-juan Zhang
    Dermal preadipocytes produce T cell chemokines in response to IFNγ, driving the recruitment and activation of type 1 effector T cells in allergic contact dermatitis.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Released bacterial ATP shapes local and systemic inflammation during abdominal sepsis

    Daniel Spari, Annina Schmid ... Guido Beldi
    Bacteria release ATP as part of their attack in sepsis.
    1. Immunology and Inflammation

    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells

    Chan-Su Park, Jian Guan ... Scheherazade Sadegh-Nasseri
    Fam49b is a critical regulator of selection process to ensure normal thymocyte development and peripheral T cells survival.
    1. Immunology and Inflammation

    IL-2 enhances effector function but suppresses follicular localization of CD8+ T cells in chronic infection

    Yaping Chen, Pengcheng Zhou ... Di Yu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Immunology and Inflammation

    Science Forum: Antibody characterization is critical to enhance reproducibility in biomedical research

    Richard A Kahn, Harvinder Virk ... Skye Longworth
    There is an ongoing need for researchers and all stakeholders to better understand issues surrounding antibody characterization to improve the quality and reproducibility of research that employs these reagents.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Vaccines: How do adjuvants enhance immune responses?

    Rekha R Rapaka
    By altering which peptide antigens are presented to CD4+ T cells, adjuvants affect the specificity of the immune response.
    Version of Record
    Insight
    1. Immunology and Inflammation

    A hepatocyte-specific transcriptional program driven by Rela and Stat3 exacerbates experimental colitis in mice by modulating bile synthesis

    Jyotsna, Binayak Sarkar ... Rajesh S Gokhale
    Studies in murine model identify hepatic Rela-Stat3 network as a potential driver of gut inflammation and a novel therapeutic target for inflammatory bowel disease, offering new insights into liver-gut crosstalk.