Browse our latest Microbiology and Infectious Disease articles

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    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex

    Clarissa L Durie et al.
    The structure of the Legionella pneumophilaType IV secretion system provides the detailed molecular model of this complex molecular machine required for pathogenesis.
    1. Microbiology and Infectious Disease

    Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex

    Michael J Sheedlo et al.
    The structure of a Type IV secretion system provides a framework for understanding assembly of a protein-injection machine.
    1. Microbiology and Infectious Disease

    The flagellar motor of Vibrio alginolyticus undergoes major structural remodeling during rotational switching

    Brittany L Carroll et al.
    In situ structures of the flagellar motors genetically docked in CCW and CW rotational states reveal major rearrangement that facilitates rotational switch in Vibrio alginolyticus..
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Poultry farmer response to disease outbreaks in smallholder farming systems in southern Vietnam

    Alexis Delabouglise et al.
    Longitudinal monitoring of poultry farms in southern Vietnam reveals that when outbreaks occur with symptoms similar to highly pathogenic avian influenza, farmers respond by sending their chickens to market early.
    1. Microbiology and Infectious Disease

    The Mla pathway in Acinetobacter baumannii has no demonstrable role in anterograde lipid transport

    Matthew J Powers et al.
    An outer membrane vesicle pulse-chase assay demonstrates that the Acinetobacter baumannii Mla system is a retrograde lipid transporter.
    1. Microbiology and Infectious Disease

    Complement opsonization of HIV affects primary infection of human colorectal mucosa and subsequent activation of T cells

    Pradyot Bhattacharya et al.
    Complement opsonized HIV exposure gives rise to a colorectal mucosal environment with an initial suppressed antiviral response and increased infection of immune cells and altered activation of T cells.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Mutational resilience of antiviral restriction favors primate TRIM5α in host-virus evolutionary arms races

    Jeannette L Tenthorey et al.
    Mutations in the TRIM5α retrovirus-binding interface frequently improve but rarely disrupt retroviral restriction.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    The NTP generating activity of pyruvate kinase II is critical for apicoplast maintenance in Plasmodium falciparum

    Russell P Swift et al.
    The pyruvate kinase contained in the apicoplast organelle of malaria parasites makes the nucleotide triphosphates required for several processes including transcription of the organellar genome.