Browse our latest Microbiology and Infectious Disease articles

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    1. Computational and Systems Biology
    2. Microbiology and Infectious Disease

    Merging multi-omics with proteome integral solubility alteration unveils antibiotic mode of action

    Ritwik Maity, Xuepei Zhang ... Javier Sancho
    Like two peas in a pod but not exactly alike, similar molecules targeting the same bacterial protein behave differently, requiring systems biology and target deconvolution to gain better comprehension.
    1. Microbiology and Infectious Disease

    Human induced pluripotent stem cell-derived cardiomyocytes to study inflammation-induced aberrant calcium transient

    Yuki Tatekoshi, Chunlei Chen ... Hossein Ardehali
    A calcium transient measurement system utilizing human induced pluripotent stem cell-derived cardiomyocytes reveals the detrimental impact of inflammatory cytokines on cardiomyocyte relaxation and displays the potential of drugs to reverse these defects.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Antigenic drift and subtype interference shape A(H3N2) epidemic dynamics in the United States

    Amanda C Perofsky, John Huddleston ... Cécile Viboud
    Antigenic drift in influenza’s major surface proteins, hemagglutinin and neuraminidase, contributes to variability in epidemic magnitude across seasons but is less influential than subtype interference in shaping annual outbreaks.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Root cap cell corpse clearance limits microbial colonization in Arabidopsis thaliana

    Nyasha M Charura, Ernesto Llamas ... Alga Zuccaro