Browse our latest Microbiology and Infectious Disease articles

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    1. Cell Biology
    2. Microbiology and Infectious Disease

    Glycolysis-dependent Sulfur Metabolism Orchestrates Morphological Plasticity and Virulence in Fungi

    Dhrumi Shah, Nikita Rewatkar ... Sriram Varahan
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease
    3. Medicine

    Focus Issue: Trained Immunity

    Edited by Satyajit Rath et al.
    Our latest Focus Issue looks at what we’ve learnt over the past decade and what’s next for the field of trained immunity.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Focus Issue: Evolving our understanding of trained immunity

    Eva Kaufmann, Yahya Sohrabi ... Jos WM van der Meer
    The articles in this focus issue discuss progress towards a more complete understanding of memory in the innate immune system, and efforts to exploit "trained immunity" for the development of new vaccines and therapeutics.
    1. Microbiology and Infectious Disease

    Quinolines interfere with heme-mediated activation of artemisinins

    Melissa R Rosenthal, Daniel E Goldberg
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Bacteriology: How Shigella tackles host defences

    Yizhou Huang, Teresa LM Thurston
    The pathogenic bacteria Shigella avoids detection inside hosts cells by degrading RNF213, the protein responsible for sensing the presence of intracellular pathogens.
    Version of Record
    Insight
    1. Microbiology and Infectious Disease

    Research advance: Unexpected plasticity in the life cycle of Trypanosoma brucei

    Carina Praisler, Jaime N Lisack ... Markus Engstler
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Solid
    1. Microbiology and Infectious Disease
    2. Computational and Systems Biology

    Automated genome mining predicts structural diversity and taxonomic distribution of peptide metallophores across bacteria

    Zachary L Reitz, Bita Pourmohsenin ... Marnix H Medema
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Microbiology and Infectious Disease

    Detecting, mapping, and suppressing the spread of a decade-long Pseudomonas aeruginosa nosocomial outbreak with genomics

    William Stribling, Lindsey R Hall ... Francois Lebreton
    Routine genomic surveillance uncovered a decades-long multidrug-resistant Pseudomonas aeruginosa outbreak sustained by patient reservoirs and hospital plumbing, enabling targeted infection control measures that ultimately curtailed transmission.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Cell membrane glycan contents are biochemical factors that constitute a kinetic barrier to viral particle uptake in a protein-nonspecific manner

    Yoshihisa Kaizuka, Rika Machida
    Intermolecular steric repulsion generated by glycans on the cell membrane inhibits viral infection by preventing the formation of a virus-cell interface, regardless of the identity of molecules for glycan modification.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders

    Matthew B McDougal, Ian N Boys ... John W Schoggins
    Evolutionary changes in RNA binding and antiviral activity result in diverse IFIT1 functions across mammals, even among closely related species.
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