Browse our latest Microbiology and Infectious Disease articles

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    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Purine nucleosides replace cAMP in allosteric regulation of PKA in trypanosomatid pathogens

    Veronica Teresa Ober, George Boniface Githure ... Michael Boshart
    A minimal subset of two to three residues in cyclic nucleotide binding (CNB) domains controls nucleoside vs. cyclic nucleotide specificity, repurposing PKA of certain pathogens for novel nucleoside signaling pathways or sensing.
    1. Microbiology and Infectious Disease

    Targeting host deoxycytidine kinase mitigates Staphylococcus aureus abscess formation

    Volker Winstel, Evan R Abt ... Caius G Radu
    Host-directed therapy neutralizes a refined immuno-evasive maneuver of pathogenic staphylococci.
    1. Microbiology and Infectious Disease
    2. Physics of Living Systems

    Potassium-mediated bacterial chemotactic response

    Chi Zhang, Rongjing Zhang, Junhua Yuan
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Proteolytic cleavage and inactivation of the TRMT1 tRNA modification enzyme by SARS-CoV-2 main protease

    Kejia Zhang, Patrick Eldin ... Dragony Fu
    1. Microbiology and Infectious Disease

    Mycobacterium tuberculosis PhoP integrates stress response to intracellular survival by maintenance of cAMP level

    Hina Khan, Partha Paul ... Dibyendu Sarkar
    1. Microbiology and Infectious Disease

    The Toxoplasma monocarboxylate transporters are involved in the metabolism within the apicoplast and are linked to parasite survival

    Hui Dong, Jiong Yang ... Shaojun Long
    Combined cutting-edge technologies discovered a pair of carboxylate transporters that appears evolutionarily different among novel transporters and that is essential for parasite physiology.
    1. Microbiology and Infectious Disease

    Small RNAs from mitochondrial genome recombination sites are incorporated into T. gondii mitoribosomes

    Sabrina Tetzlaff, Arne Hillebrand ... Christian Schmitz-Linneweber
    Sequences at mitochondrial genome recombination sites are dually used as mRNAs and as rRNAs in actively translating mitoribosomes of T. gondii.
    1. Microbiology and Infectious Disease

    Architecture of genome-wide transcriptional regulatory network reveals dynamic functions and evolutionary trajectories in Pseudomonas syringae

    Yue Sun, Jingwei Li ... Xin Deng
    1. Microbiology and Infectious Disease

    Maintenance of cell wall remodeling and vesicle production are connected in Mycobacterium tuberculosis

    Vivian Salgueiro, Jorge Bertol ... Rafael Prados-Rosales
    1. Medicine
    2. Microbiology and Infectious Disease

    Gut microbiota-derived gamma-aminobutyric acid from metformin treatment reduces hepatic ischemia/reperfusion injury through inhibiting ferroptosis

    Fangyan Wang, Xiujie Liu ... Wantie Wang
    Gut microbiota-derived gamma-aminobutyric acid is identified as a key metabolite that metformin protect from hepatic ischemia/reperfusion injury.
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