Browse our latest Microbiology and Infectious Disease articles

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    1. Microbiology and Infectious Disease
    2. Ecology

    Expanding the toolbox: Novel class IIb microcins show activity against Gram-negative ESKAPE and plant pathogens

    Benedikt M Mortzfeld, Shakti K Bhattarai, Vanni Bucci
    Not yet revised
    Reviewed Preprint v1
    1. Microbiology and Infectious Disease

    Cell-autonomous targeting of arabinogalactan by host immune factors inhibits mycobacterial growth

    Lianhua Qin, Junfang Xu ... Haipeng Liu
    Galectin-9 directly binds to arabinogalactan (AG), leading to the identification of AG-specific monoclonal antibodies that effectively inhibit Mycobacterium tuberculosis growth, providing insights for novel tuberculosis therapies.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Reassessing the substrate specificities of the major Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM

    Lina Antenucci, Salla Virtanen ... Perttu Permi
    Robust NMR approach allowed simultaneous detection of substrate cleavage site and real-time kinetics of hydrolysis for Staphylococcus aureus peptidoglycan hydrolases lysostaphin and LytM, and revealed D-alanyl-glycine activity for LytM.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Proteostasis modulates gene dosage evolution in antibiotic-resistant bacteria

    Chinmaya Jena, Saillesh Chinnaraj ... Nishad Matange
    Not yet revised
    Reviewed Preprint v1
    1. Microbiology and Infectious Disease

    RNase III in Salmonella Enteritidis enhances bacterial virulence by reducing host immune responses

    Bill Kwan-wai Chan, Yingxue Li ... Sheng Chen
    Not yet revised
    Reviewed Preprint v1
    1. Microbiology and Infectious Disease

    HIV-1 Vif disrupts phosphatase feedback regulation at the kinetochore, leading to a pronounced pseudo-metaphase arrest

    Dhaval A Ghone, Edward L Evans ... Aussie Suzuki
    Not yet revised
    Reviewed Preprint v1
    1. Microbiology and Infectious Disease

    Regulative synthesis of capsular polysaccharides in the pathogenesis of Streptococcus suis

    Xingye Wang, Jie Wang ... Beinan Wang
    Not yet revised
    Reviewed Preprint v1
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    PRR adjuvants restrain high stability peptides presentation on APCs

    Bin Li, Jin Zhang ... Chao Wu
    Adjuvants, MPLA and CpG especially, modulate the peptide repertoires presented on the surface of APCs, preferring the presentation of low-affinity exogenous peptides rather than high-affinity peptides.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Whole blood transcriptional profiles and the pathogenesis of tuberculous meningitis

    Hoang Thanh Hai, Le Thanh Hoang Nhat ... Nguyen Thuy Thuong Thuong
    An unbiased transcriptomic analysis enhances understanding of inflammatory pathways and genes linked to TBM pathogenesis and mortality, identifying potential markers for poor prognosis or therapeutic targets.
    1. Microbiology and Infectious Disease
    2. Evolutionary Biology

    A suite of selective pressures supports the maintenance of alleles of a Drosophila immune peptide

    Sarah R Mullinax, Andrea M Darby ... Robert L Unckless
    Revised
    Reviewed Preprint v2 Updated
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