Browse our latest Microbiology and Infectious Disease articles

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    1. Microbiology and Infectious Disease

    Parasites: Eviction notice served on Toxoplasma

    Juan C Sánchez-Arcila, Kirk DC Jensen
    The gene RARRES3 uses an unexpected strategy to eliminate the parasite Toxoplasma gondii from human cells.
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    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Transcriptional correlates of malaria in RTS,S/AS01-vaccinated African children: a matched case–control study

    Gemma Moncunill et al.
    Prevaccination levels of transcriptional modules related to monocytes, dendritic cells, and other immune categories correlate with clinical malaria risk in RTS,S/AS01E-vaccinated African children, suggesting that certain monocyte subsets may inhibit RTS,S/AS01E-induced protective responses.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Absolute quantitation of individual SARS-CoV-2 RNA molecules provides a new paradigm for infection dynamics and variant differences

    Jeffrey Y Lee et al.
    Single-molecule analysis of SARS-CoV-2 RNA identifies significant heterogeneity in cellular viral RNA levels and highlights slower replication kinetics for the Alpha variant compared to the Victoria strain.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis

    Thomas Laval et al.
    Infection with Mycobacterium tuberculosis triggers de novo synthesis of polyunsaturated fatty acids by host macrophages, which promote their antimicrobial responses but feed the intracellular pathogen.
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Human MAIT cells respond to and suppress HIV-1

    Chansavath Phetsouphanh et al.
    In depth phenotyping from tissues and in vitro activation studies reveal antiviral function of MAIT cells- with particular emphasis on HIV infection.