Browse our latest Microbiology and Infectious Disease articles

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    1. Microbiology and Infectious Disease

    Evolution of a functionally intact but antigenically distinct DENV fusion loop

    Rita M Meganck, Deanna Zhu ... Longping V Tse
    Operating as a serum profiling tool for dengue infection and vaccination, the D2-FLM variant, which is insensitive to antibody-dependent enhancement-prone fusion loop antibodies, also offers potential for a safer dengue virus vaccine.
    1. Microbiology and Infectious Disease

    Biosensor-integrated transposon mutagenesis reveals rv0158 as a coordinator of redox homeostasis in Mycobacterium tuberculosis

    Somnath Shee, Reshma T Veetil ... Amit Singh
    Genome-scale integration of transposon mutagenesis with a redox biosensor identified a hypothetical transcription factor- Rv0158 required to calibrate the growth, cytoplasmic redox potential, and respiration of Mycobacterium tuberculosis in response to metabolic switching from glucose to fatty acids.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 Salmonella Typhi genomes

    Megan E Carey, Zoe A Dyson ... Global Typhoid Genomics Consortium Group Authorship
    An analysis of the largest Salmonella Typhi genome collection to date (n=13,000) provides an updated overview of global genome diversity and antimicrobial resistance trends over time to inform public health action.
    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Influenza virus transcription and progeny production are poorly correlated in single cells

    David J Bacsik, Bernadeta Dadonaite ... Jesse D Bloom
    Quantification of both viral transcription and progeny production from single influenza-infected cells shows that the cells that produce the most viral RNA often do not produce the most virions.
    1. Epidemiology and Global Health
    2. Microbiology and Infectious Disease

    COVID-19 and Cancer: Acting on past lessons and learning new ones

    Eduardo L Franco, Diane M Harper
    eLife has published a special issue containing articles that examine how cancer prevention, control, care and survivorship were impacted by the COVID-19 pandemic.
    Editorial
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