Browse our latest Microbiology and Infectious Disease articles

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    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Rapid adaptation of a complex trait during experimental evolution of Mycobacterium tuberculosis

    Tracy M Smith et al.
    Mycobacterium tuberculosis, which causes tuberculosis, can evolve rapidly in response to new environments by mutating genetic regulators that control multiple genes at once.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    An M protein coiled coil unfurls and exposes its hydrophobic core to capture LL-37

    Piotr Kolesinski et al.
    Streptococcus pyogenes M87 protein unfurls its coiled coil to capture and neutralize the human antimicrobial peptide LL-37.
    1. Microbiology and Infectious Disease

    Lactococcus lactis NCDO2118 exerts visceral antinociceptive properties in rat via GABA production in the gastro-intestinal tract

    Valérie Laroute et al.
    Generally recognised as safe GABA-producing L. lactis strains could be considered as future therapeutic agents for the management of visceral pain and the anxious profile of IBS patients.
    1. Microbiology and Infectious Disease

    WhyD tailors surface polymers to prevent premature bacteriolysis and direct cell elongation in Streptococcus pneumoniae

    Josué Flores-Kim et al.
    Selective removal of Wall Teichoic Acids from the envelope of Streptococcus pneumoniae prevents bacteriolysis and directs zonal cell wall synthesis.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Ancestral reconstruction of duplicated signaling proteins reveals the evolution of signaling specificity

    Isabel Nocedal, Michael T Laub
    Ancestral reconstruction of a signaling pathway reveals the mutations responsible for producing specificity of the two paralogous pathways produced by a duplication event.
    1. Microbiology and Infectious Disease

    NAD kinase promotes Staphylococcus aureus pathogenesis by supporting production of virulence factors and protective enzymes

    Clarisse Leseigneur et al.
    Staphylococcus aureus NAD kinase promotes infection by protecting bacteria from host antimicrobial defenses and by supporting production of major virulence factors.
    1. Ecology
    2. Microbiology and Infectious Disease

    Humanization of wildlife gut microbiota in urban environments

    Brian A Dillard et al.
    Urban wildlife harbor gut bacteria found in humans but missing from rural wildlife, consistent with bacterial transmission from humans to wildlife in cities.