Browse our latest Microbiology and Infectious Disease articles

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    1. Microbiology and Infectious Disease

    Machine learning approaches identify immunologic signatures of total and intact HIV DNA during long-term antiretroviral therapy

    Lesia Semenova, Yingfan Wang ... Edward P Browne
    Dimension reduction and machine learning tools were used to identify novel associations between the HIV reservoir and the immune systems of people with HIV.
    1. Microbiology and Infectious Disease

    Rifampicin tolerance and growth fitness among isoniazid-resistant clinical Mycobacterium tuberculosis isolates from a longitudinal study

    Srinivasan Vijay, Nguyen Le Hoai Bao ... Nguyen Thuy Thuong
    Isoniazid resistance in Mycobacterium tuberculosis is linked to higher rifampicin tolerance, necessitating evaluation and potential adjustment of treatment regimens to combat emerging multi-drug resistant variants.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Recombinant origin and interspecies transmission of a HERV-K(HML-2)-related primate retrovirus with a novel RNA transport element

    Zachary H Williams, Alvaro Dafonte Imedio ... Welkin E Johnson
    The genetic 'fossil record' of a retroviral lineage over >25 million years of evolution reveals the profound consequences of an ancient recombination event on viral replication mechanisms and genome structure, and identifies an ancient interspecies viral transmission.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Reversions mask the contribution of adaptive evolution in microbiomes

    Paul A Torrillo, Tami D Lieberman
    The timescale dependence of dN/dS in bacteria is better explained by adaptive than purifying dynamics, suggesting comparative genomics can underestimate past adaptation.
    1. Microbiology and Infectious Disease

    Unraveling CRP/cAMP-Mediated Metabolic Regulation In Escherichia coli Persister Cells

    Han G Ngo, Sayed Golam Mohiuddin ... Mehmet A Orman
    1. Microbiology and Infectious Disease

    The effect of combining antibiotics on resistance: A systematic review and meta-analysis

    Berit Siedentop, Viacheslav N Kachalov ... Sebastian Bonhoeffer