Electrochemical recordings of cortico-striatal glutamatergic signaling, and chemogenetic inhibition of such signaling, revealed an essential role of cortico-striatal input for cued action selection, but not for cued stopping.
Seemingly disparate property-based tasks (oddball search, same-different and symmetry) are solved by computing a novel image property, visual homogeneity, which is localized to the object selective cortex.
The Apollo implant, an open-source device tested in eight laboratories, can be used to reversibly implant Neuropixels probes and track the activity of populations of neurons across days.
Predictive pharmacology based on behavioural fingerprinting can identify druggable pathways that are altered or renormalized in zebrafish larvae that harbor mutations in early and late-onset Alzheimer's disease risk genes.
Ana Fló, Lucas Benjamin ... Ghislaine Dehaene-Lambertz
Human neonates process regularities in speech's phonetic and voice content in parallel, but only phonetic regularities evoke a specific ERP component in a post-learning phase.
Kaspar E Vogt, Ashwinikumar Kulkarni ... Robert W Greene
Sleep's role to down-scale glutamate, excitatory, frontal cortical synapses is extended to include an up-scaling of metaplastic LTP potential, in recovery from prolonged waking induced saturation of this LTP potential.
Christopher Bell, Lukas Kilo ... Stefanie Ryglewski
Mutually exclusive splicing of two exon pairs of the only Drosophila Cav2 homolog cacophony mediates functional diversity of Cav2 channels in Drosophila.
A data-driven exploration of amygdala microstructure captures this region's subnuclear structure and dissociates its cortical functional connectivity profiles.