Browse our latest Neuroscience articles

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    1. Medicine
    2. Neuroscience

    A latent clinical-anatomical dimension relating metabolic syndrome to brain structure and cognition

    Marvin Petersen, Felix Hoffstaedter ... Bastian Cheng
    Structural neuroimaging of 40,087 individuals identifies a distinct brain morphological profile associated with metabolic syndrome, linking cardiometabolic risk to cognitive performance, microscale tissue composition, and macroscale brain network architecture.
    1. Neuroscience

    Distinctive whole-brain cell types predict tissue damage patterns in thirteen neurodegenerative conditions

    Veronika Pak, Quadri Adewale ... Yasser Iturria-Medina
    Major cell types across various brain regions distinctively associate with tissue loss in 13 neurodegenerative conditions.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons

    Ayumu Mubuchi, Mina Takechi ... Shinji Miyata
    The extracellular matrix formed during embryonic brain development facilitates the migration of cortical neurons.
    1. Neuroscience

    Memory-specific encoding activities of the ventral tegmental area dopamine and GABA neurons

    Vasileios Glykos, Shigeyoshi Fujisawa
    Dopamine and GABA neurons in the ventral tegmental area encode short-term memory in the T-maze task, which cannot be explained by reward-related processes, motivated behavior, or motor-related activities.
    1. Neuroscience

    The stability of the primed pool of synaptic vesicles and the clamping of spontaneous neurotransmitter release rely on the integrity of the C-terminal half of the SNARE domain of syntaxin-1A

    Andrea Salazar Lázaro, Thorsten Trimbuch ... Christian Rosenmund
    Structure–function studies on the synaptic vesicle release protein syntaxin-1 identified structural motifs on the surface of the SNARE complex controlling vesicle priming and spontaneous release unique for synaptic signaling.
    1. Neuroscience

    Comparative brain-wide mapping of ketamine- and isoflurane-activated nuclei and functional networks in the mouse brain

    Yue Hu, Wenjie Du ... Yingwei Wang
    Brain-wide activation patterns reveal the distinct and shared neurophysiological impacts of ketamine and isoflurane, highlighting key nuclei involved in the modulation of general anesthesia.
    1. Neuroscience

    Heterosynaptic plasticity of the visuo-auditory projection requires cholecystokinin released from entorhinal cortex afferents

    Wenjian Sun, Haohao Wu ... Jufang He
    Visuo-auditory associative memories in the neocortex are formed through cholecystokinin-mediated heterosynaptic plasticity, primarily involving entorhinal cortex projections to the auditory cortex, highlighting intricate neural dynamics in multisensory memory processing.
    1. Neuroscience

    A previously undescribed scene-selective site is the key to encoding ego-motion in naturalistic environments

    Bryan Kennedy, Sarala N Malladi ... Shahin Nasr
    There are many fine-scale scene-selective areas within the visual system, beyond the occipital, temporal, and medial place areas, whose function may be key to performing complex tasks in dynamic environments.
    1. Neuroscience

    Rho GTPase signaling and mDia facilitate endocytosis via presynaptic actin

    Kristine Oevel, Svea Hohensee ... Volker Haucke
    Genetic and pharmacological tools are used to dissect the mechanisms by which the presynaptic actin cytoskeleton facilitates membrane internalization at synapses and, thereby, neurotransmission.
    1. Neuroscience

    Establishment of transgenic fluorescent mice for labeling synapses and screening synaptogenic adhesion molecules

    Lei Yang, Jingtao Zhang ... Chen Zhang
    A Syt1-tdTomato transgenic mice with normal synaptic transmission is established to label synapse in situ and screen synaptogenic adhesion molecules.