Browse our latest Neuroscience articles

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    1. Neuroscience

    Speech and music recruit frequency-specific distributed and overlapping cortical networks

    Noémie te Rietmolen, Manuel R Mercier ... Daniele Schön
    The neural response to natural speech and music processing is mostly shared between the domains, with additional evidence for selectivity in distributed (i.e. not regional) and frequency-specific neural activity.
    1. Neuroscience

    Using synchronized brain rhythms to bias memory-guided decisions

    John J Stout, Allison E George ... Amy L Griffin
    Brain-machine interfacing was used to align trials with heightened prefrontal-hippocampal oscillatory synchronization on spatial working memory-dependent and -independent tasks, and these trials were associated with correct choices.
    1. Developmental Biology
    2. Neuroscience

    Energetic demands regulate sleep-wake rhythm circuit development

    Amy R Poe, Lucy Zhu ... Matthew S Kayser
    Behavioral and circuit analyses show that changes to energetic demand are a key driver of consolidation of daily sleep and feeding patterns as animals mature.
    1. Neuroscience

    Firing rate adaptation affords place cell theta sweeps, phase precession, and procession

    Tianhao Chu, Zilong Ji ... Si Wu
    Adaptation within a continuous attractor neural network explains theta phase precession and procession, providing insight into the neural mechanism of theta phase coding in the hippocampus.
    1. Neuroscience

    Neural activity ramps in frontal cortex signal extended motivation during learning

    Josue M Regalado, Ariadna Corredera Asensio ... Priyamvada Rajasethupathy
    Motivated animals learn to put in more effort and ignore distractions to reach their goals due to increased neural activity in the frontal cortex.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Alzheimer’s disease linked Aβ42 exerts product feedback inhibition on γ-secretase impairing downstream cell signaling

    Katarzyna Marta Zoltowska, Utpal Das ... Lucía Chávez-Gutiérrez
    A novel Aβ-driven inhibitory mechanism on γ-secretases, which leads to substrate accumulation and reduced release of products, contributes to neurotoxicity by impairing γ-secretase signaling and might operate in Alzheimer’s disease.
    1. Computational and Systems Biology
    2. Neuroscience

    Myelin dystrophy impairs signal transmission and working memory in a multiscale model of the aging prefrontal cortex

    Sara Ibañez, Nilapratim Sengupta ... Christina M Weaver
    Biologically plausible levels of myelin dystrophy induce substantial working memory impairment in a computational model of brain aging across two spatial and temporal scales.
    1. Neuroscience

    Prediction error determines how memories are organized in the brain

    Nicholas GW Kennedy, Jessica C Lee ... Nathan M Holmes
    When new and past experiences are similar, the memories of those experiences are stored together, and when new and past experiences are different, the memories of those experiences are stored separately.
    1. Neuroscience

    An allocentric human odometer for perceiving distances on the ground plane

    Liu Zhou, Wei Wei ... Zijiang J He
    Fitting our terrestrial niche, the human visual system adopts a ground-based reference frame for spatial computation in concert with the attention, memory, and path-integration processes for space perception during self-motion.
    1. Neuroscience

    Non-Hebbian plasticity transforms transient experiences into lasting memories

    Islam Faress, Valentina Khalil ... Sadegh Nabavi
    The process of transformation of a transient experience into a memory is neither restricted to the time of the experience nor to the synapses triggered by it, but it can be influenced by past and future events.