Browse our latest Neuroscience articles

Inhibitory circuit motifs in the mouse brain and the human brain are strikingly similar.

Linguistic features are encoded more strongly during language comprehension than when comprehension is absent, and high word entropy (less constraining context) enhances the encoding of lower-level acoustic and linguistic features while low word entropy suppresses it.

The α₁-adrenergic receptor augments the activity of the L-type Ca²⁺ channel Ca_V1.2 through PKC and the tyrosine kinases Pyk2 and Src and thereby synaptic plasticity.

Recurrent neural networks trained to navigate and infer latent states exhibit strikingly similar remapping patterns to those observed in navigational brain areas, inspiring new analyses of published data and suggesting a possible function for spontaneous remapping to support context-dependent navigation.

Connectomics of the octopus 'fan-out fan-in’ learning network reveals that the intermediate layer uses approximately 22×10⁶ excitatory interneurons, each can store a single sensory input, while approximately 400×10³ integrating inhibitory interneurons adjust the network output level.

A laboratory experiment provides the first evidence that framing a sham treatment as personalised to one's genetics and physiology increases its placebo effect on pain.

Ketamine induces the expression of Ca²⁺-permeable AMPA receptors to enhance synaptic glutamatergic and Ca²⁺ activity in neurons to cause rapid antidepressant effects.

Cerebral subcortical microcirculation is more vulnerable to aging-induced changes and more responsive to exercise than cortical microcirculation.

Opioids have distributed effects on the brainstem circuitry that controls breathing, including presynaptic and postsynaptic receptor-mediated inhibition of an excitatory circuit from the dorsolateral pons to the ventrolateral medulla.

Close friend quantity is nonlinearly associated with various mental health and cognitive outcomes in children and could be partly explained by the structure of the social brain and the endogenous opioid system.