Brad K Hulse, Hannah Haberkern ... Vivek Jayaraman
An analysis of the first complete synaptic resolution connectome of Drosophila's navigation circuit uncovers neural network motifs supporting broadly relevant sensorimotor computations.
Philip J O'Herron, David A Hartmann ... Andy Y Shih
The diameter of individual or multiple arterioles can be rapidly controlled with high spatiotemporal resolution using optogenetics, providing a technique for the direct manipulation of blood flow independently of neural activity or pharmacological agents.
In vivo imaging reveals that the synaptic vesicle cycle is a significant contributor to oxidative stress in sensory hair cells, rendering them susceptible to insults.
Cecilia Gallego-Carracedo, Matthew G Perich ... Juan Álvaro Gallego
There is a frequency-dependent association between the local field potential and the coordinated activity of populations of single neurons, which remains constant during different aspects of behaviour but changes across regions of primate sensorimotor cortex.
Electrophysiological recordings in awake behaving monkeys show the first evidence of the effect of continuous theta-burst stimulation, a widely used repetitive transcranial magnetic stimulation protocol, at the level of single neurons.
Task controllability manipulations reveal that information seeking is associated with reduced confidence and active hypothesis testing, as well as stronger neurophysiological correlates of attention and arousal.
Luc Edward Wilson, Jason da Silva Castanheira, Sylvain Baillet
The new method and reported findings address a growing interest in neuroscience for research tools that can reliably decompose brain activity at the mesoscopic scale into interpretable components.