The immunoglobulin superfamily cell surface protein Sticks and Stones is a binding partner for the Lar Drosophila receptor tyrosine phosphatase that mediates Lar's developmental functions at the larval neuromuscular junction, mushroom body, and adult optic lobe.
Eszter Szabó, Cinzia Chiandetti ... Giorgio Vallortigara
Without specific training, young chicks represent the absence of objects, showing that the concept of 'nothing' is available to nonhuman animals and does not require linguistic tools, such as negation.
Rolando Masís-Obando, Kenneth A Norman, Christopher Baldassano
Neural representations of both general event schemas and story-specific details predict memory performance in narrative recall, with distinct brain networks tracking schematic information during perception versus retrieval.
The proposed method deciphers which low-level patterns (such as spikes) control high-level features (behavior) in relative small biological datasets, taking into account the statistical dependencies between such patterns.
In order to homeostatically regulate many (n) properties at the same time, neurons must coadjust many (n + 1) ion channels with the appropriate ratios, which can lead to ion channel correlations and increased risk of regulation failure.
Sofia Lövestam, Fujiet Adrian Koh ... Sjors HW Scheres
Laboratory-based methods are presented that produce filamentous tau aggregates with the same structures as those observed in neurodegenerative disease.
Alexandria MH Lesicko, Christopher F Angeloni ... Maria N Geffen
A specific neuronal pathway within the auditory system represents information about the statistical prediction and error for incoming sounds, thereby contributing to efficient representation of complex sounds and sound streams in the brain.
Andrew T Landau, Pojeong Park ... Bernardo L Sabatini
Elaborate dendritic branch patterns lead to a local and branch-specific reduction in impedance, which attenuates back-propagating action potentials and limits voltage-gated calcium influx.
Evripidis Gkanias, Li Yan McCurdy ... Barbara Webb
Modelling differential roles for identified dopaminergic and output neurons of the fruit fly mushroom bodies, combined with a novel dopaminergic plasticity rule, explains neural and behavioural phenomena in olfactory learning tasks.
