Browse our latest Neuroscience articles

Prelimbic cortical inputs are differentially recruited during early memory consolidation, with claustrum projections involved at encoding and insular cortex projections recruited for recent recall.

The brain’s projection of linguistic knowledge onto speech is reflected by the automatic, reflexive neural tracking of phrases, while the distribution of phrasal-rate tracking and connectivity, particularly the involvement of inferior frontal cortex, is subject to task demands.

Electrophysiological and genetic analyses reveal a biophysical mechanism in parvalbumin interneurons, uncoupled from changes in gene expression, resulting in reduced cortical inhibition in early-stage Alzheimer's disease.

Hypothalamic stress effector neurons rapidly change activity patterns via recurrent inhibition, representing state-dependent activity switch between baseline and elevated stress levels.

By acting as versatile signal-processors that encode flexible coordinate representations, muscle spindles challenge current widely held views concerning the role of proprioceptors and the peripheral nervous system in sensorimotor function.

Among three new models for KCNMA1 channelopathy, the most severe gain-of-function variant (Kcnma1^N999S/WT) displays a particular type of immobilizing paroxysmal dyskinesia observed in patients, including amphetamine responsiveness.

The majority of hippocampal neurons in CA3 experience inhibition before and during ripple buildup, while dentate and CA1 cells display depolarizing transients preceding and following ripple onset pointing to a long and orchestrated awake ripple initiation process.

Comprehensive multi-neuron fluorescence imaging in C. elegans reveals age-associated changes in neuronal activity that include a breakdown of system-wide organization, changes in neuronal frequency dynamics, and a disruption of the balance between excitatory and inhibitory signaling.

The circadian clock gates sleep drive by modulating sleep homeostat neurons.

Fewer neurons and more glia than previously predicted plus substantial differences between males and females are revealed when entire intact Drosophila larval central nervous systems are quantified using a synthesis of genetic, imaging, and computation technologies.