Embryonic PI3K-Yap activity regulates apical adhesion and proliferation of neural progenitors lining the lateral ventricular surface, to maintain the smooth, non-folded mouse brain and to prevent developmental hydrocephalus.
Mary L Phillips, Holly Anne Robinson, Lucas Pozzo-Miller
Input from the ventral hippocampus to the medial prefrontal cortex regulates social memory in wild type mice and atypically-strengthened input causes social memory dysfunction in Rett syndrome mice.
William T Birdsong, Bart C Jongbloets ... Tianyi Mao
By differentially modulating the two major excitatory inputs to the striatum, mu- and delta-opioid receptors regulate the balance between thalamic and cortical inputs to the striatum.
Frauke Ackermann, Kay Oliver Schink ... Craig Curtis Garner
The active zone protein Piccolo regulates efficient recycling of SVs via Pra1 and Rab5 and is therefore critical for integrity and reliability of synaptic function.
Janine Diane Bijsterbosch, Christian F Beckmann ... Samuel J Harrison
The estimation of functional connectivity network matrices from resting state fMRI is driven by a combination of spatial and temporal factors in the presence of spatially overlapping network structure.
Biologically plausible changes in the excitabilities of single neurons may suffice to selectively modulate sequential network dynamics, without modifying of recurrent connectivity.
Salvador Dura-Bernal, Benjamin A Suter ... William W Lytton
The NetPyNE software tool provides a framework to efficiently develop, simulate, optimize and analyze experimentally grounded neural models spanning the molecular, cellular and circuit scales.
The important role of serine biosynthesis in Müller cells may explain why the macula is so much more prone to developing disease than the rest of the retina.
Action-selection under response-conflict is buttressed by an inhibitory control signal from the basal ganglia that non-selectively suppresses motor excitability.
