Browse our latest Neuroscience articles

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    1. Neuroscience

    A kinase-dependent feedforward loop affects CREBB stability and long term memory formation

    Pei-Tseng Lee, Guang Lin ... Hugo J Bellen
    Through an image and behavioral screen based on MiMIC technology, we identified a novel kinase, CG11221 renamed Meng-Po (MP), and showed that flies that lack MP in mushroom bodies can learn but cannot remember as MP is required for the protein stability of CREBB.
    1. Neuroscience

    Orphan receptor GPR158 controls stress-induced depression

    Laurie P Sutton, Cesare Orlandi ... Kirill A Martemyanov
    The orphan receptor GPR158 is highly regulated by stress exposure and acts on key neuronal signaling pathways in the prefrontal cortex to control depressive-like behaviors.
    1. Medicine
    2. Neuroscience

    Dopamine-dependent scaling of subthalamic gamma bursts with movement velocity in patients with Parkinson’s disease

    Roxanne Lofredi, Wolf-Julian Neumann ... Andrea A Kühn
    Bradykinesia in Parkinson's disease may be associated to a dopamine-dependent recruitment failure of subthalamic activity in short bursts of gamma synchrony.
    1. Neuroscience

    The modulation of neural gain facilitates a transition between functional segregation and integration in the brain

    James M Shine, Matthew J Aburn ... Russell A Poldrack
    The flexible network architecture of the brain is sensitive to the modulation of neural gain, which may be mediated by ascending arousal nuclei, such as the noradrenergic locus coeruleus.
    1. Neuroscience

    Role of the visual experience-dependent nascent proteome in neuronal plasticity

    Han-Hsuan Liu, Daniel B McClatchy ... Hollis T Cline
    A screen of visual-experience induced changes in newly-synthesized proteins in Xenopus optic tectum identifies unexpected candidate plasticity proteins.
    1. Cell Biology
    2. Neuroscience

    Time- and polarity-dependent proteomic changes associated with homeostatic scaling at central synapses

    Christoph T Schanzenbächer, Julian D Langer, Erin M Schuman
    Metabolic labelling and quantitative proteomics reveal the temporal evolution of cellular and neuronal responses to global activity manipulations.
    1. Neuroscience

    Multi-neuron intracellular recording in vivo via interacting autopatching robots

    Suhasa B Kodandaramaiah, Francisco J Flores ... Craig R Forest
    A robot capable of automatically obtaining blind whole cell patch clamp recordings from multiple neurons simultaneously guides four interacting electrodes in a coordinated fashion, avoiding mechanical coupling in the brain.
    1. Neuroscience

    Suppression and facilitation of human neural responses

    Michael-Paul Schallmo, Alexander M Kale ... Scott O Murray
    Spatial suppression during motion perception reflects reduced neural response magnitudes in visual areas but is not primarily driven by neural inhibition.
    1. Neuroscience

    Internal amino acid state modulates yeast taste neurons to support protein homeostasis in Drosophila

    Kathrin Steck, Samuel J Walker ... Carlos Ribeiro
    Two different classes of taste receptor neurons in the Drosophila melanogaster proboscis play distinct roles in yeast feeding and are both modulated by the fly's internal amino acid state in order to promote protein-specific appetite.
    1. Neuroscience

    The representational dynamics of task and object processing in humans

    Martin N Hebart, Brett B Bankson ... Radoslaw M Cichy
    Task representations emerge rapidly throughout human cortex, with parallel object representations in occipitotemporal cortex that are increasingly dominated by task in higher visual areas.