Browse our latest Neuroscience articles

Page 507 of 644
    1. Cell Biology
    2. Neuroscience

    KIF2A regulates the development of dentate granule cells and postnatal hippocampal wiring

    Noriko Homma, Ruyun Zhou ... Nobutaka Hirokawa
    Postnatal KIF2A is a key regulator for axon/dendrite determination of developing dentate granule cells, and its loss developed apical axons in dentate molecular layer, broke hippocampal wiring, and induced temporal lobe epilepsy.
    1. Neuroscience

    Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling

    Mengchen Ye, Kathryn M Lehigh, David D Ginty
    Multivesicular bodies deliver long-range retrograde nerve growth factor (NGF) signals and serve as essential signaling and sorting platforms in the cell soma, and multivesicular body (MVB) cargoes dictate their vesicular fate.
    1. Computational and Systems Biology
    2. Neuroscience

    Inferring multi-scale neural mechanisms with brain network modelling

    Michael Schirner, Anthony Randal McIntosh ... Petra Ritter
    Hybrid brain network models predict neurophysiological processes that link structural and functional empirical data across scales and modalities in order to better understand neural information processing and its relation to brain function.
    1. Neuroscience

    Persistent activity in a recurrent circuit underlies courtship memory in Drosophila

    Xiaoliang Zhao, Daniela Lenek ... Krystyna Keleman
    Persistent activity of dopaminergic neurons in a mushroom recurrent circuit lays the foundation for courtship memory in Drosophila.
    1. Neuroscience

    miR-9 regulates basal ganglia-dependent developmental vocal learning and adult vocal performance in songbirds

    Zhimin Shi, Zoe Piccus ... XiaoChing Li
    Gene manipulation combined with behavior analysis reveals a role of miR-9 in modulating basal-ganglia-dependent developmental vocal learning and adult vocal performance via regulating the FOXP1/FOXP2 gene network and dopamine signaling in songbirds.
    1. Neuroscience

    Hypocretin underlies the evolution of sleep loss in the Mexican cavefish

    James B Jaggard, Bethany A Stahl ... Alex C Keene
    The identification of evolutionarily-derived changes in Hypocretin function within the brains of short-sleeping Mexican cavefish provides a system for investigating the mechanistic basis of sleep differences throughout the animal kingdom.
    1. Neuroscience

    Thalamocortical and corticothalamic pathways differentially contribute to goal-directed behaviors in the rat

    Fabien Alcaraz, Virginie Fresno ... Mathieu Wolff
    Adaptive decision-making critically depends on antiparallel flows conveying distinct information within thalamocortical circuits, highlighting directionality of functional exchanges as a neural principle potentially at play in virtually any brain circuit with reciprocal projections.
    1. Neuroscience

    Activity-induced Ca2+ signaling in perisynaptic Schwann cells of the early postnatal mouse is mediated by P2Y1 receptors and regulates muscle fatigue

    Dante J Heredia, Cheng-Yuan Feng ... Thomas W Gould
    A genetic strategy reveals that the perisynaptic glial response to neural activity in one population of these glia regulates postsynaptic function and therefore muscle fatigue.
    1. Cell Biology
    2. Neuroscience

    The synaptic ribbon is critical for sound encoding at high rates and with temporal precision

    Philippe Jean, David Lopez de la Morena ... Tobias Moser
    The synaptic ribbon regulates calcium channel clustering and proper vesicle dynamics at cochlear inner hair cells to ensure precise sound encoding.
    1. Neuroscience

    The presynaptic ribbon maintains vesicle populations at the hair cell afferent fiber synapse

    Lars Becker, Michael E Schnee ... Anthony J Ricci
    The auditory hair cell synaptic ribbon maintains vesicle pools near release sites in order to support sustained and timed vesicle release.