Browse our latest Neuroscience articles

Page 508 of 644
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Molecular structure of human KATP in complex with ATP and ADP

    Kenneth Pak Kin Lee, Jue Chen, Roderick MacKinnon
    MgADP binding to the high-affinity 'consensus' ATPase active site of SUR1 and remodeling of the L0-loop (lasso region) overrides tonic ATP inhibition of KATP channels.
    1. Neuroscience

    Inhibition of oxidative stress in cholinergic projection neurons fully rescues aging-associated olfactory circuit degeneration in Drosophila

    Ashiq Hussain, Atefeh Pooryasin ... Ilona C Grunwald Kadow
    Drosophila genetics and behavior reveal that oxidative stress induced axonal degeneration in a single class of neurons drives the functional decline of an entire neural network and the behavior it controls.
    1. Neuroscience

    Neuronal populations in the occipital cortex of the blind synchronize to the temporal dynamics of speech

    Markus Johannes Van Ackeren, Francesca M Barbero ... Olivier Collignon
    Blind people re-purpose the brain's visual areas for tracking speech rhythm.
    1. Neuroscience

    Neuronal activity determines distinct gliotransmitter release from a single astrocyte

    Ana Covelo, Alfonso Araque
    A single astrocyte can decode neuronal activity and, consequently, release distinct gliotransmitters that differentially regulate neurotransmission at single hippocampal synapses.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Piezo Ion Channels: Portraits of a pressure sensor

    Alexander T Chesler, Marcin Szczot
    Near atomic-resolution structures have provided insights into the mechanisms by which the Piezo1 ion channel senses and responds to mechanical stimuli.
    Version of Record
    Insight
    1. Neuroscience

    BAD and KATP channels regulate neuron excitability and epileptiform activity

    Juan Ramón Martínez-François, María Carmen Fernández-Agüera ... Gary Yellen
    Altered activity of ATP-sensitive K+ channels underlies the metabolic seizure resistance produced by genetic manipulation of the BAD protein in mice.
    1. Neuroscience

    Human subthalamic nucleus activity during non-motor decision making

    Baltazar A Zavala, Anthony I Jang, Kareem A Zaghloul
    Intraoperative human brain recordings during a memory task reveal that when participants inhibit memory formation, the subthalamic nucleus shows higher beta power and beta coherence with areas of the lateral cortex implicated in memory processing.
    1. Neuroscience

    Distributed rhythm generators underlie Caenorhabditis elegans forward locomotion

    Anthony D Fouad, Shelly Teng ... Christopher Fang-Yen
    The forward locomotor circuit of the roundworm Caenorhabditis elegans consists of multiple rhythm-generating units coupled to one another in a bidirectional manner.
    1. Neuroscience

    Excitatory motor neurons are local oscillators for backward locomotion

    Shangbang Gao, Sihui Asuka Guan ... Mei Zhen
    Motor neurons are rhythm generators for backward locomotion.
    1. Neuroscience

    Tracing neuronal circuits in transgenic animals by transneuronal control of transcription (TRACT)

    Ting-hao Huang, Peter Niesman ... Carlos Lois
    A new method that will allow researchers to visualize and genetically manipulate synaptically connected neurons in a brain circuit.