Browse our latest Neuroscience articles

Page 515 of 599
    1. Neuroscience

    Asymmetric effects of activating and inactivating cortical interneurons

    Elizabeth AK Phillips, Andrea R Hasenstaub
    The consequences of manipulating neuronal activity with techniques such as optogenetics are highly sensitive to methodological details, highlighting the need for caution when interpreting results.
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    PtdInsP2 and PtdSer cooperate to trap synaptotagmin-1 to the plasma membrane in the presence of calcium

    Ángel Pérez-Lara, Anusa Thapa ... Reinhard Jahn
    Two acidic membrane lipids increase synaptotagmin-1 dwell time and penetration into the membrane, reducing the membrane dissociation of synaptotagmin-1.
    1. Cell Biology
    2. Neuroscience

    Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3'-end processing

    Piergiorgio La Rosa, Pamela Bielli ... Claudio Sette
    The RNA binding protein Sam68 links a key metabolic route to the neural stem cell fate in the developing mouse brain.
    1. Neuroscience
    2. Developmental Biology

    Neuroendocrine modulation sustains the C. elegans forward motor state

    Maria A Lim, Jyothsna Chitturi ... Mei Zhen
    RID is a descending peptidergic neuron that sustains the forward motor state.
    1. Neuroscience

    Visual attention is available at a task-relevant location rapidly after a saccade

    Tao Yao, Madhura Ketkar ... B Suresh Krishna
    Spatial attention and saccadic processing co-ordinate to ensure that attention is available at a task-relevant location soon after the beginning of each eye fixation.
    1. Neuroscience

    Postprandial sleep mechanics in Drosophila

    Keith R Murphy, Sonali A Deshpande ... William W Ja
    Evidence of food coma has been found in fruit flies, allowing the properties that drive postprandial sleep and their underlying genetic and neuronal mechanisms to be described.
    1. Neuroscience

    Chronic social isolation reduces 5-HT neuronal activity via upregulated SK3 calcium-activated potassium channels

    Derya Sargin, David K Oliver, Evelyn K Lambe
    Serotonin neurons in chronically isolated mice become less responsive to excitatory stimulation, but inhibiting a distinctive calcium-activated potassium channel can restore both neuronal activity and behavior.
    1. Neuroscience

    SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise

    Teppei Fujikawa, Carlos M Castorena ... Joel K Elmquist
    The transcription factor steroidogenic factor-1 in the hypothalamus is required for adaptive metabolic responses to exercise training.
    1. Neuroscience

    Profound alteration in cutaneous primary afferent activity produced by inflammatory mediators

    Kristen M Smith-Edwards, Jennifer J DeBerry ... C Jeffery Woodbury
    Inflammatory pain, previously thought to result from increased activity in "pain" neurons, may in fact be due to wholesale changes in afferent output that includes increased and decreased activity that the brain interprets as pain.
    1. Cell Biology
    2. Neuroscience

    Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies

    Wei-Hua Lee, Hitoshi Higuchi ... Akihiro Ikeda
    The murine protein TMEM135 is a critical link between aging and age-dependent diseases.