Browse our latest Neuroscience articles

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    1. Neuroscience

    The information bottleneck as a principle underlying multi-area cortical representations during decision-making

    Michael Kleinman, Tian Wang ... Jonathan C Kao
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Neuroscience

    Consciousness: Did you see it?

    Ling Liu
    Cautious reporting choices can artificially enhance how well analyses of brain activity reflect conscious and unconscious experiences, making distinguishing between the two more challenging.
    Version of Record
    Insight
    1. Neuroscience

    Criterion placement threatens the construct validity of neural measures of consciousness

    Johannes Jacobus Fahrenfort, Philippa A Johnson ... Simon van Gaal
    The neural basis of consciousness is confounded by the mismatch between what participants report about their experience versus what they actually experience.
    1. Neuroscience

    Endogenous oscillatory rhythms and interactive contingencies jointly influence infant attention during early infant-caregiver interaction

    Emily AM Phillips, Louise Goupil ... Sam V Wass
    Infant attention during naturalistic social interactions is supported by their own endogenous neural activity and extended with the micro-contingent behavioural responsivity of their caregiver.
    1. Neuroscience

    Quantification of the effect of hemodynamic occlusion in two-photon imaging of mouse cortex

    Baba Yogesh, Matthias Heindorf ... Georg B Keller
    Hemodynamic occlusion introduces a spatially heterogenous confound to activity measurements using two-photon and widefield imaging in mouse cortex, and needs to be taken into consideration when interpreting functional imaging data.
    1. Medicine
    2. Neuroscience

    Diet modulates the therapeutic effects of dimethyl fumarate mediated by the immunometabolic neutrophil receptor HCAR2

    Joanna Kosinska, Julian C Assmann ... Markus Schwaninger
    The therapeutic effect of dimethyl fumarate in experimental autoimmune encephalomyelitis depends on the diet of mice and is mediated by the G protein-coupled receptor HCAR2 in neutrophils.
    1. Neuroscience

    Integration of head and body orientations in the macaque superior temporal sulcus is stronger for upright bodies

    Yordanka Zafirova, Rufin Vogels
    Head and body orientation cues are integrated by macaque superior temporal sulcus neurons, with stronger integration for upright monkey images.
    1. Neuroscience

    An antisense oligonucleotide-based strategy to ameliorate cognitive dysfunction in the 22q11.2 Deletion Syndrome

    Pratibha Thakur, Martin Lackinger ... Joseph A Gogos
    Targeting EMC10 restores neuronal function in 22q11.2DS patient-derived neurons and reverses cognitive deficits in adult mice, highlighting its potential as a therapeutic strategy for mitigating disease-related cognitive impairments.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    A Kv2 inhibitor combination reveals native neuronal conductances consistent with Kv2/KvS heteromers

    Robert G Stewart, Matthew James Marquis ... Jon T Sack
    Drugs are identified that unmask molecular origins of certain neuronal potassium currents, enabling functional analysis of previously indistinguishable potassium channel subtypes.
    1. Developmental Biology
    2. Neuroscience

    Commissureless acts as a substrate adapter in a conserved Nedd4 E3 ubiquitin ligase pathway to promote axon growth across the midline

    Kelly G Sullivan, Greg J Bashaw
    Commissureless works with the Nedd4 E3 ubiquitin ligase to transiently degrade the Robo1 receptor to allow commissural axons to cross the midline.
    Version of Record
    Research Article
    • Fundamental
    • Compelling
    • Convincing