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    1. Neuroscience

    Esr1-Dependent Signaling and Transcriptional Maturation in the Medial Preoptic Area of the Hypothalamus Shapes the Development of Mating Behavior during Adolescence

    Koichi Hashikawa, Yoshiko Hashikawa ... Garret D Stuber
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    1. Neuroscience

    Neural geometry from mixed sensorimotor selectivity for predictive sensorimotor control

    Yiheng Zhang, Yun Chen ... He Cui
    Target motion modulates monkey M1 neural dynamics during reaching, characterized by an orbital neural geometry composed of target-velocity-dependent tilting rings, suggesting that sensory information can be independently incorporated during motor generation.
    1. Neuroscience

    GPRC6A as a novel kokumi receptor responsible for enhanced taste preferences by ornithine

    Takashi Yamamoto, Kayoko Ueji ... Shinya Ugawa
    The enhanced taste and flavor of food induced by the addition of L-ornithine, referred to as 'kokumi' in humans, may be mediated by GPRC6A receptors expressed in taste cells.
    1. Neuroscience

    Perceptual and attentional impairments of conscious access involve distinct neural mechanisms despite equal task performance

    Samuel Noorman, Timo Stein ... Simon van Gaal
    When performance is matched, the attentional blink allows for greater integration of complex stimulus features than masking, reflecting spared recurrent processing during attentional versus perceptual impairments of conscious access.
    1. Evolutionary Biology
    2. Neuroscience

    The first complete 3D reconstruction and morphofunctional mapping of an insect eye

    Anastasia A Makarova, Nicholas J Chua ... Alexey A Polilov
    Even the smallest compound eyes retain the functional specialization of ommatidia.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Affinity-guided labeling reveals P2X7 nanoscale membrane redistribution during microglial activation

    Benoit Arnould, Adeline Martz ... Thomas Grutter
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    cxcl18b-defined transitional state-specific nitric oxide drives injury-induced Müller glia cell-cycle re-entry in the zebrafish retina

    Aojun Ye, Shuguang Yu ... Chang Chen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Neuroscience

    Multiplexed CRISPRi Reveals a Transcriptional Switch Between KLF Activators and Repressors in the Maturing Neocortex

    Ryan W Kirk, Liwei Sun ... Sacha Nelson
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Neuroscience

    Untangling stability and gain modulation in cortical circuits with multiple interneuron classes

    Hannah Bos, Christoph Miehl ... Brent Doiron
    In recurrently connected cortical networks with different inhibitory neuron subtypes, circuit modulations can increase neuronal gain without compromising network stability.
    1. Genetics and Genomics
    2. Neuroscience

    Antagonist actions of CMK-1/CaMKI and TAX-6/calcineurin along the C. elegans thermal avoidance circuit orchestrate adaptation of nociceptive response to repeated stimuli

    Martina Rudgalvyte, Zehan Hu ... Dominique A Glauser
    Phosphoproteomics identifies diverse CaM kinase substrates, while genetic dissection reveals an unexpected antagonistic interaction with calcineurin signaling that operates in distinct neurons to regulate thermo-nociception in Caenorhabditis elegans.
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