Browse our latest Neuroscience articles

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    1. Neuroscience

    Successful retrieval of competing spatial environments in humans involves hippocampal pattern separation mechanisms

    Colin T Kyle, Jared D Stokes ... Arne D Ekstrom
    Functional magnetic resonance imaging and multivariate pattern analysis reveal remapping-like behavior during successful retrieval of competing environments, while unsuccessful retrieval is accompanied by reinstatement of interfering representations.
    1. Neuroscience

    Lateral orbitofrontal neurons acquire responses to upshifted, downshifted, or blocked cues during unblocking

    Nina Lopatina, Michael A McDannald ... Geoffrey Schoenbaum
    Building on previous work (McDannald et. al, 2014), it is shown that dissociable populations of neurons in the lateral orbitofrontal cortex acquire responses to cues that predict more, less, or no change in reward in rats during training in a Pavlovian unblocking task.
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation

    Andreu Viader, Daisuke Ogasawara ... Benjamin F Cravatt
    Cell-specific pathways regulate lipid transmitters and neuroinflammation in the brain.
    1. Ecology
    2. Neuroscience

    Burst muscle performance predicts the speed, acceleration, and turning performance of Anna’s hummingbirds

    Paolo S Segre, Roslyn Dakin ... Douglas L Altshuler
    Maneuverability is thought to be limited by either intrinsic constraints or physiological capacity, and automated tracking of flying hummingbirds reveals that muscle capacity explains much of the variation in their flight trajectories.
    1. Neuroscience

    IK1 channels do not contribute to the slow afterhyperpolarization in pyramidal neurons

    Kang Wang, Pedro Mateos-Aparicio ... John P Adelman
    The slow afterhyperpolarization that follows a burst of action potentials is a powerful regulator of neuronal excitability and is not due to IK1 (KCNN4), a member of the SK channel family.
    1. Neuroscience

    Striatal dynamics explain duration judgments

    Thiago S Gouvêa, Tiago Monteiro ... Joseph J Paton
    Neurons in the rat striatum respond preferentially to long or short time intervals, enabling the animal to track the passage of time.
    1. Neuroscience

    Rhythmic coordination of hippocampal neurons during associative memory processing

    Lara M Rangel, Jon W Rueckemann ... Howard Eichenbaum
    Different rhythms uniquely contribute to task-related processing in the hippocampus, and changes in the rhythmic profile of the hippocampus reflect dynamic coordination of its cell activity.
    1. Neuroscience

    Capturing the temporal evolution of choice across prefrontal cortex

    Laurence T Hunt, Timothy EJ Behrens ... Steven W Kennerley
    Experiments in macaques and humans reveal time-varying changes in prefrontal cortex activity that occur during decisions based on costs and benefits.
    1. Genetics and Genomics
    2. Neuroscience

    Temporal transcriptomics suggest that twin-peaking genes reset the clock

    William G Pembroke, Arran Babbs ... Peter L Oliver
    RNA sequencing reveals the finer details of circadian variation in the mammalian master pacemaker over 24 hours, which suggests that transcriptional timing influences clock resetting mechanisms.
    1. Neuroscience

    Optimal level activity of matrix metalloproteinases is critical for adult visual plasticity in the healthy and stroke-affected brain

    Justyna Pielecka-Fortuna, Evgenia Kalogeraki ... Siegrid Löwel
    Matrix metalloproteinases play a crucial role in adult visual plasticity in the brains of healthy and stroke-affected mice and their activity has to be within a narrow window for experience-induced plasticity to occur.