Johannes Jacobus Fahrenfort, Philippa A Johnson ... Simon van Gaal
The neural basis of consciousness is confounded by the mismatch between what participants report about their experience versus what they actually experience.
Infant attention during naturalistic social interactions is supported by their own endogenous neural activity and extended with the micro-contingent behavioural responsivity of their caregiver.
Hemodynamic occlusion introduces a spatially heterogenous confound to activity measurements using two-photon and widefield imaging in mouse cortex, and needs to be taken into consideration when interpreting functional imaging data.
Joanna Kosinska, Julian C Assmann ... Markus Schwaninger
The therapeutic effect of dimethyl fumarate in experimental autoimmune encephalomyelitis depends on the diet of mice and is mediated by the G protein-coupled receptor HCAR2 in neutrophils.
Pratibha Thakur, Martin Lackinger ... Joseph A Gogos
Targeting EMC10 restores neuronal function in 22q11.2DS patient-derived neurons and reverses cognitive deficits in adult mice, highlighting its potential as a therapeutic strategy for mitigating disease-related cognitive impairments.
Robert G Stewart, Matthew James Marquis ... Jon T Sack
Drugs are identified that unmask molecular origins of certain neuronal potassium currents, enabling functional analysis of previously indistinguishable potassium channel subtypes.
Sara A Nolin, Mary E Faulkner ... Kristina M Visscher
Greater differentiation of brain networks is a hallmark of good cognitive functioning among individuals who have avoided neurodegenerative disease and live longer than a typical human lifespan.
Subcortical brain structures contain neurons encoding subjective reports of stimulus detection in human participants, suggesting a role for conscious perception.